X-VIR 0.5MG TAB. 1X30 TAB.

About

Entecavir is an oral antiviral agent belonging to the class of nucleoside analogues, specifically designed for the treatment of chronic hepatitis B virus (HBV) infection. It works by inhibiting HBV reverse transcriptase, an enzyme essential for viral replication, thereby reducing viral load and improving liver function. Entecavir is highly potent and generally well-tolerated, making it a cornerstone in the long-term management of chronic HBV, including in patients with compensated or decompensated liver disease. Its efficacy in suppressing viral replication helps to prevent disease progression, reduce the risk of cirrhosis, hepatocellular carcinoma, and liver-related mortality. Regular monitoring of liver function, viral load, and renal function is crucial during therapy to assess efficacy and manage potential side effects, ensuring sustained viral suppression.

Uses

• Chronic hepatitis B infection.
• HBV with compensated liver disease.
• HBV with decompensated liver disease.
• Prevention of HBV reactivation.

Directions For Use

Take orally once daily on an empty stomach (at least 2 hours after and 2 hours before a meal).

Benefits

• Potent antiviral activity against HBV.
• Reduces HBV viral load.
• Improves liver histology.
• Low risk of drug resistance.
• Well-tolerated for long-term use.
• Reduces risk of liver complications.

Side Effects

• Headache
• Fatigue
• Dizziness
• Nausea
• Diarrhea
• Dyspepsia
• Insomnia
• Abdominal pain
• Elevated liver enzymes
• Lactic acidosis (rare)
• Hepatomegaly with steatosis (rare)
• Renal impairment (rare)

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it can worsen liver disease and interfere with treatment.
• Pregnancy - Use only if the potential benefit justifies the potential risk to the fetus; consult a specialist.
• Breastfeeding - Not recommended due to potential for serious adverse effects in the infant.
• Liver - Use with caution in decompensated liver disease; monitor closely for lactic acidosis.
• Kidney - Dosage adjustment is required for patients with renal impairment.
• Lung - No specific contraindication; generally safe for use in patients with lung conditions.

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