ZOCEF 500 6S

About

ZOCEF 500, containing Cefuroxime 500mg, is a second-generation cephalosporin antibiotic. It exerts its bactericidal action by inhibiting the synthesis of the bacterial cell wall, leading to the lysis and death of susceptible bacteria. Cefuroxime is effective against a broad spectrum of gram-positive and gram-negative bacteria, including many strains resistant to first-generation cephalosporins. Its stability against many beta-lactamases, enzymes produced by bacteria that can inactivate antibiotics, contributes to its efficacy. This antibiotic is widely used to treat various bacterial infections across different body systems, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, and ear infections. Its oral formulation provides a convenient and effective treatment option for both adults and children, ensuring good patient compliance and therapeutic outcomes.

Uses

• Treatment of respiratory tract infections (e.g., bronchitis, pneumonia).
• Management of urinary tract infections.
• Therapy for skin and soft tissue infections.
• Treatment of ear, nose, and throat infections (e.g., otitis media, sinusitis).

Directions For Use

Take orally with food, as directed by your physician, to enhance absorption and minimize gastrointestinal upset.

Benefits

• Broad-spectrum antibiotic activity.
• Effective against a wide range of bacteria.
• Good tissue penetration.
• Convenient dosing regimen.
• Generally well-tolerated.
• Treats common bacterial infections effectively.

Side Effects

• Nausea and vomiting.
• Diarrhea or abdominal pain.
• Headache.
• Dizziness.
• Skin rash or itching.
• Candidiasis (yeast infection).
• Allergic reactions (e.g., urticaria).
• Elevated liver enzymes.
• Kidney dysfunction (rare).
• Clostridium difficile infection (rare).
• Eosinophilia.
• Positive Coombs' test.

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it may increase gastrointestinal side effects such as nausea and vomiting.
• Pregnancy - Generally considered safe, but use only if clearly needed and potential benefits outweigh risks. Consult a doctor.
• Breastfeeding - Generally considered safe, but monitor infant for potential diarrhea, thrush, or allergic reactions.
• Liver - Use with caution in severe impairment; no major dose adjustment usually needed, but monitor liver function.
• Kidney - Dose adjustment is necessary in patients with impaired kidney function to prevent accumulation and toxicity.
• Lung - Generally safe, but caution in patients with severe asthma or a history of penicillin allergy due to cross-reactivity risk.

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