AMCHEK-AT 10S

About

Amlodipine and Atenolol is a combination medication primarily utilized for the comprehensive management of essential hypertension and certain forms of chronic stable angina pectoris. Amlodipine, a dihydropyridine calcium channel blocker, exerts its therapeutic effect by promoting peripheral vasodilation, thereby reducing systemic vascular resistance and lowering blood pressure. It also improves myocardial oxygen supply, alleviating angina. Atenolol, a beta-1 selective adrenergic blocker, acts by reducing heart rate, myocardial contractility, and cardiac output, which further contributes to blood pressure reduction and decreases the heart's oxygen demand. This synergistic action provides a robust and sustained antihypertensive and antianginal effect, making it particularly beneficial for patients who require multi-modal pharmacological intervention to achieve optimal cardiovascular control or those whose conditions are not adequately managed by monotherapy. Prescribing this combination necessitates a thorough clinical evaluation to ensure suitability and minimize potential adverse effects.

Uses

• Management of essential hypertension.
• Treatment of chronic stable angina pectoris.
• Prevention of angina attacks.
• Adjunctive therapy in certain cardiovascular conditions.

Directions For Use

Take as directed by your physician, usually once daily with or without food. Do not crush or chew the tablet.

Benefits

• Effective blood pressure reduction.
• Improved control of angina symptoms.
• Reduced risk of cardiovascular events.
• Convenient once-daily dosing.
• Dual mechanism of action for comprehensive control.
• Well-established efficacy in hypertension management.

Side Effects

• Dizziness or lightheadedness
• Fatigue or weakness
• Swelling in ankles or feet (edema)
• Headache
• Nausea
• Bradycardia (slow heart rate)
• Cold hands and feet
• Shortness of breath
• Insomnia or sleep disturbances
• Muscle cramps
• Depression
• Sexual dysfunction

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it can increase the hypotensive effects and worsen dizziness.
• Pregnancy - Generally not recommended during pregnancy, especially in the second and third trimesters, due to potential fetal harm. Consult a doctor.
• Breastfeeding - Atenolol is excreted in breast milk and may cause adverse effects in the infant. Use with caution and medical advice.
• Liver - Use with caution in patients with liver impairment; dosage adjustments may be necessary.
• Kidney - Dosage adjustments are often required in patients with renal dysfunction. Close monitoring is essential.
• Lung - Atenolol should be used with extreme caution in patients with bronchial asthma or other bronchospastic conditions.

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