About
ESPIN, containing Amlodipine, is a long-acting dihydropyridine calcium channel blocker primarily used in the management of hypertension and various forms of angina. It works by relaxing the smooth muscles in the walls of blood vessels, leading to vasodilation and a reduction in peripheral vascular resistance. This action effectively lowers blood pressure and improves blood flow to the heart, thereby reducing the workload on the heart and alleviating angina symptoms. Amlodipine is characterized by its gradual onset and prolonged duration of action, allowing for convenient once-daily dosing. Its efficacy in reducing cardiovascular events in hypertensive patients, improving exercise tolerance in angina patients, and its generally favorable tolerability profile make it a widely prescribed and effective medication for long-term cardiovascular management.
Uses
- Treatment of hypertension (high blood pressure).
- Management of chronic stable angina pectoris.
- Treatment of vasospastic angina (Prinzmetal's angina).
- To reduce the risk of hospitalization for angina in patients with coronary artery disease.
Directions For Use
Take one tablet orally once daily, with or without food, as prescribed by your doctor.
Benefits
- Effectively lowers elevated blood pressure.
- Reduces the frequency and severity of angina attacks.
- Improves exercise tolerance in patients with angina.
- Provides a long-lasting effect, allowing for once-daily dosing.
- Well-tolerated by most patients.
- Can be used alone or in combination with other antihypertensive agents.
Side Effects
- Peripheral edema (swelling of ankles/feet)
- Headache
- Dizziness
- Flushing
- Fatigue
- Palpitations
- Nausea
- Abdominal pain
- Somnolence (drowsiness)
- Rash
- Muscle cramps
- Gingival hyperplasia (gum overgrowth)
Safety Measures
- Alcohol - Alcohol can enhance the blood pressure-lowering effect of Amlodipine, potentially leading to dizziness or fainting. Use with caution.
- Pregnancy - Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. Consult your doctor.
- Breastfeeding - Amlodipine is excreted in breast milk. Use with caution and consult your doctor before breastfeeding.
- Liver - Amlodipine is extensively metabolized by the liver. Dose adjustment may be necessary in patients with severe hepatic impairment. Consult your doctor.
- Kidney - No dose adjustment is typically required for patients with renal impairment. Generally considered safe for kidney conditions.
- Lung - No direct contraindications related to lung conditions. Generally considered safe for patients with respiratory issues.
Disclaimer
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