Aspezex 10000IU Injection

About

Human Chorionic Gonadotropin (hCG) is a naturally occurring glycoprotein hormone, predominantly synthesized by the placenta during pregnancy, playing a critical role in maintaining the corpus luteum. In clinical practice, pharmaceutical preparations of hCG, whether recombinant or derived from purified human urine, are utilized for their ability to mimic the actions of luteinizing hormone (LH). In women, hCG is instrumental in triggering ovulation in cases of anovulatory infertility and is also employed to support the luteal phase in assisted reproductive technologies, thereby enhancing the chances of successful implantation and early pregnancy maintenance. For men, hCG stimulates the Leydig cells in the testes to produce testosterone and promotes spermatogenesis, making it valuable in treating hypogonadotropic hypogonadism. Its therapeutic effects are mediated by binding to LH receptors, which subsequently stimulates steroidogenesis and facilitates the maturation of gametes.

Uses

• Induction of ovulation in women
• Treatment of male hypogonadotropic hypogonadism
• Stimulation of spermatogenesis
• Support of luteal phase in IVF

Directions For Use

Administer subcutaneously or intramuscularly as directed by a physician. Dosage and frequency depend on the specific indication and patient response.

Benefits

• Induces ovulation
• Stimulates testosterone production
• Promotes spermatogenesis
• Supports early pregnancy
• Effective in fertility treatments
• Mimics natural LH action

Side Effects

• Injection site reactions (pain, bruising)
• Headache
• Irritability
• Restlessness
• Fatigue
• Breast tenderness
• Ovarian hyperstimulation syndrome (OHSS) in women
• Gynecomastia in men
• Abdominal pain
• Nausea
• Vomiting
• Mood changes

Safety Measures

• Alcohol - No specific interaction with alcohol is known, but it's generally advisable to limit alcohol intake during fertility treatments.
• Pregnancy - Used to support early pregnancy or induce ovulation. Not for use once pregnancy is confirmed, unless specifically for luteal support.
• Breastfeeding - Not typically recommended during breastfeeding as its effects on breastfed infants are not well-established.
• Liver - Use with caution in patients with severe liver impairment. Liver function should be monitored if concerns arise.
• Kidney - Use with caution in patients with severe kidney impairment. Excretion may be altered, requiring dose adjustment.
• Lung - No specific contraindications related to lung conditions, but monitor for symptoms of thromboembolism, a rare but serious side effect.

Disclaimer

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