About
Pancrelipase is a pancreatic enzyme replacement therapy (PERT) containing a mixture of lipase, amylase, and protease, derived from porcine pancreatic glands. It is crucial for individuals suffering from exocrine pancreatic insufficiency (EPI), a condition characterized by the pancreas's inability to produce sufficient digestive enzymes. EPI commonly arises from conditions such as cystic fibrosis, chronic pancreatitis, pancreatic surgery, or pancreatic cancer. The enzymes in pancrelipase work synergistically in the small intestine to break down dietary fats, carbohydrates, and proteins into smaller, absorbable molecules.
This therapeutic intervention is vital for improving nutrient absorption and mitigating the debilitating symptoms associated with maldigestion, such as steatorrhea, abdominal discomfort, bloating, and weight loss. Effective management with pancrelipase significantly enhances the patient's nutritional status and overall quality of life by ensuring proper digestion and absorption of essential nutrients.
Uses
- Exocrine pancreatic insufficiency (EPI)
- Cystic fibrosis-related malabsorption
- Chronic pancreatitis
- Pancreatic surgery-induced enzyme deficiency
Directions For Use
Take orally with meals and snacks, as directed by a physician. Do not crush or chew capsules; swallow whole.
Benefits
- Improves digestion of fats, carbohydrates, and proteins.
- Reduces symptoms of malabsorption like steatorrhea.
- Enhances nutrient absorption and nutritional status.
- Alleviates abdominal pain and bloating.
- Supports healthy weight maintenance.
- Improves overall quality of life for EPI patients.
Side Effects
- Abdominal pain
- Nausea
- Diarrhea
- Constipation
- Bloating
- Flatulence
- Headache
- Dizziness
- Skin rash
- Allergic reactions (rare)
- Fibrosing colonopathy (very rare, high doses)
- Increased uric acid levels
Safety Measures
- Alcohol - Alcohol consumption can exacerbate pancreatic conditions and may reduce the effectiveness of pancreatic enzymes. It is generally advised to limit or avoid alcohol.
- Pregnancy - Generally considered safe, but use only if clearly needed and under medical supervision. Consult a doctor.
- Breastfeeding - Pancreatic enzymes are not expected to pass into breast milk. Considered compatible with breastfeeding, but consult a healthcare provider.
- Liver - No specific dose adjustment is typically required for liver impairment. Use with caution in severe liver disease if associated with pancreatic issues.
- Kidney - No specific dose adjustment is typically required for kidney impairment. Use with caution in severe kidney disease.
- Lung - No direct impact on lung function. Safe for use in patients with lung conditions, including cystic fibrosis.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
Our goal is to complement, not replace, the essential doctor-patient relationship.
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| Shop Location | Assam, India |
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