Piclib 100mg Capsule

About

Piclib 100mg Capsule is a targeted antineoplastic agent designed to selectively inhibit specific molecular pathways involved in cancer cell growth and proliferation. It functions by blocking the activity of certain enzymes, such as kinases, which are often overactive in various types of malignancies. This targeted approach helps to disrupt the signaling cascades that drive tumor development, leading to reduced cell division and increased apoptosis (programmed cell death) in cancerous cells, while minimizing harm to healthy tissues compared to traditional chemotherapy.

The precise mechanism of action involves binding to the ATP-binding site of its target enzyme, thereby preventing phosphorylation and subsequent activation of downstream proteins essential for tumor survival. This leads to cell cycle arrest and inhibition of angiogenesis, further impeding tumor progression. Piclib 100mg Capsule is typically used in specific cancer types where the target pathway is identified as a key driver of the disease, often confirmed through biomarker testing.

Uses

• Treatment of advanced solid tumors with specific genetic mutations.
• Management of certain hematological malignancies.
• Adjuvant therapy in selected early-stage cancers.
• Part of combination regimens for metastatic disease.

Directions For Use

Take Piclib 100mg Capsule orally, once daily, with or without food, as directed by your oncologist. Do not crush, chew, or open the capsule.

Benefits

• Targets specific cancer pathways.
• May offer improved response rates in selected patients.
• Potentially fewer systemic side effects than conventional chemotherapy.
• Oral administration for convenience.
• Can be used in combination with other therapies.
• Helps to slow disease progression.

Side Effects

• Fatigue
• Nausea
• Diarrhea
• Rash
• Headache
• Abdominal pain
• Decreased appetite
• Elevated liver enzymes
• Myelosuppression (low blood counts)
• Peripheral edema
• Hypertension
• Muscle pain

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it may exacerbate certain side effects or interact with the medication.
• Pregnancy - Piclib is contraindicated in pregnancy due to potential fetal harm. Effective contraception is required during treatment and for a period after.
• Breastfeeding - Breastfeeding is not recommended during treatment with Piclib and for a specified period after the last dose, due to potential harm to the infant.
• Liver - Use with caution in patients with hepatic impairment; dose adjustments may be necessary. Regular liver function monitoring is crucial.
• Kidney - Use with caution in patients with renal impairment; dose adjustments may be required. Monitor kidney function throughout treatment.
• Lung - Monitor for new or worsening respiratory symptoms, as interstitial lung disease or pneumonitis can be rare but serious side effects.

Disclaimer

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