Glioz 250mg Capsule

About

Glioz 250mg Capsule contains temozolomide, an oral alkylating agent primarily used in the treatment of certain types of brain tumors. This medication exerts its therapeutic effect by interfering with the DNA of cancer cells, leading to DNA damage and subsequent cell death. It is particularly effective because it can cross the blood-brain barrier, allowing it to reach tumor cells within the central nervous system.

Glioz is commonly prescribed for newly diagnosed glioblastoma multiforme, often in combination with radiation therapy, and for refractory anaplastic astrocytoma. Its mechanism of action involves methylation of DNA, which triggers apoptotic pathways in rapidly dividing cancer cells, thereby inhibiting tumor growth and progression.

Uses

• Treatment of newly diagnosed glioblastoma multiforme
• Treatment of refractory anaplastic astrocytoma
• Chemotherapy for certain malignant gliomas
• Management of advanced brain tumors

Directions For Use

Take orally on an empty stomach, usually once daily for a specific number of days per cycle, as prescribed by an oncologist. Swallow capsules whole with water.

Benefits

• Oral administration for patient convenience
• Effectively crosses the blood-brain barrier
• Proven efficacy against certain brain tumors
• Can improve progression-free survival
• Used in combination with radiation therapy
• Relatively well-tolerated compared to some other chemotherapies

Side Effects

• Nausea
• Vomiting
• Fatigue
• Headache
• Constipation
• Alopecia (hair loss)
• Myelosuppression (low blood counts)
• Rash
• Anorexia (loss of appetite)
• Dizziness
• Diarrhea
• Opportunistic infections

Safety Measures

• Alcohol - Avoid alcohol due to potential for increased gastrointestinal upset, nausea, and liver strain.
• Pregnancy - Contraindicated; causes fetal harm. Women of childbearing potential must use effective contraception during and after treatment.
• Breastfeeding - Contraindicated; unknown if excreted in milk, but potential for serious adverse effects in the infant.
• Liver - Use with caution in severe hepatic impairment; monitor liver function tests regularly.
• Kidney - Use with caution in severe renal impairment; monitor kidney function tests regularly.
• Lung - Monitor for signs of interstitial pneumonitis, a rare but serious pulmonary adverse effect.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.