About
Atorvastatin, commonly known by brand names like ATORFIT, is a widely prescribed medication belonging to the class of drugs called statins. It works by inhibiting HMG-CoA reductase, an enzyme critical for cholesterol synthesis in the liver. By blocking this enzyme, atorvastatin effectively reduces the production of cholesterol, particularly low-density lipoprotein cholesterol (LDL-C), often referred to as 'bad' cholesterol. This action leads to a significant decrease in circulating LDL-C levels and also helps to lower triglycerides and slightly increase high-density lipoprotein cholesterol (HDL-C).
Atorvastatin is primarily used for the treatment of hypercholesterolemia and dyslipidemia, aiming to reduce the risk of cardiovascular events such as heart attack, stroke, and angina. It is indicated for patients with established atherosclerotic cardiovascular disease, type 2 diabetes, or multiple risk factors for coronary heart disease. Treatment with atorvastatin is typically lifelong and should be accompanied by lifestyle modifications, including a healthy diet and regular exercise, to achieve optimal therapeutic outcomes and prevent disease progression.
Uses
- Reduces high cholesterol (hypercholesterolemia).
- Prevents heart attack and stroke.
- Manages dyslipidemia.
- Reduces cardiovascular risk in high-risk patients.
Directions For Use
Take one tablet orally once daily, with or without food, preferably at the same time each day. Follow your doctor's instructions precisely.
Benefits
- Significantly lowers LDL-C levels.
- Reduces risk of major cardiovascular events.
- Helps prevent stroke.
- Lowers triglyceride levels.
- May slightly increase HDL-C.
- Stabilizes atherosclerotic plaques.
Side Effects
- Muscle pain (myalgia).
- Joint pain (arthralgia).
- Diarrhea.
- Nausea.
- Headache.
- Fatigue.
- Insomnia.
- Elevated liver enzymes.
- Abdominal pain.
- Indigestion.
- Urinary tract infection.
- Memory impairment (rare).
Safety Measures
- Alcohol - Limit alcohol intake due to increased risk of liver problems; consult a doctor.
- Pregnancy - Contraindicated; can cause fetal harm. Use effective contraception.
- Breastfeeding - Contraindicated; unknown if excreted in human milk and potential for serious adverse effects.
- Liver - Contraindicated in active liver disease; monitor liver function tests regularly.
- Kidney - Generally safe; no dose adjustment needed for mild to moderate impairment.
- Lung - Generally safe; no specific contraindications for lung conditions.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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