Bdrelin 11.25mg Injection

About

Bdrelin 11.25mg Injection is a synthetic analogue of gonadotropin-releasing hormone (GnRH), designed for sustained release to achieve chemical castration. Upon initial administration, it causes a transient surge in pituitary gonadotropin release (LH and FSH), leading to a temporary increase in sex hormone levels. However, continuous exposure to the GnRH analogue desensitizes the pituitary gland's GnRH receptors, resulting in a profound and sustained downregulation of LH and FSH secretion. This ultimately leads to a significant reduction in the production of estrogen from the ovaries and testosterone from the testes.

This sustained suppression of sex hormones is therapeutically beneficial for managing hormone-dependent conditions. The 11.25mg dose is typically formulated for extended-release, providing consistent hormonal control over several months. By effectively lowering circulating sex hormone levels, Bdrelin helps to inhibit the growth of hormone-sensitive tumors and alleviate symptoms associated with various gynecological and prostate conditions, offering a convenient and effective treatment option.

Uses

• Advanced prostate cancer.
• Endometriosis.
• Uterine fibroids.
• Central precocious puberty.

Directions For Use

Administer as a subcutaneous injection by a healthcare professional, typically once every three months or as prescribed.

Benefits

• Sustained suppression of sex hormones.
• Effective in hormone-sensitive cancers.
• Long duration of action (e.g., 3-month formulation).
• Reduces frequency of injections.
• Alleviates symptoms of endometriosis and fibroids.
• Provides consistent hormonal control.

Side Effects

• Hot flashes
• Sweating
• Headache
• Mood changes
• Decreased libido
• Vaginal dryness (in women)
• Erectile dysfunction (in men)
• Injection site reactions (pain, redness)
• Bone density loss (long-term)
• Weight gain
• Nausea
• Fatigue

Safety Measures

• Alcohol - No specific interaction with alcohol, but general health advice to limit intake applies.
• Pregnancy - Contraindicated during pregnancy due to the risk of fetal harm; ensure a negative pregnancy test before starting treatment.
• Breastfeeding - Not recommended during breastfeeding as it may interfere with lactation and could potentially harm the infant.
• Liver - Use with caution in patients with liver impairment; no specific dose adjustment typically required but monitor for adverse effects.
• Kidney - Generally safe for use in patients with kidney conditions; no dose adjustment typically required.
• Lung - No specific contraindications related to lung conditions; generally safe for use.

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