Celofos 1gm Injection

About

Celofos Injection, available in 1gm and 2gm strengths, is a broad-spectrum cephalosporin antibiotic used to treat a wide range of serious bacterial infections. It works by inhibiting bacterial cell wall synthesis, a critical process for bacterial survival, leading to the death of susceptible bacteria. This mechanism makes it highly effective against both Gram-positive and Gram-negative bacteria, including many common pathogens responsible for severe respiratory tract infections, complicated urinary tract infections, skin and soft tissue infections, bone and joint infections, and sepsis. Celofos is typically administered parenterally, making it suitable for severe infections or when oral administration is not feasible. Its long half-life allows for convenient once-daily dosing in many cases, simplifying treatment regimens and improving patient compliance in hospital and outpatient settings.

Uses

• Lower respiratory tract infections
• Urinary tract infections
• Skin and soft tissue infections
• Sepsis

Directions For Use

Administer intravenously or intramuscularly as directed by a healthcare professional. Reconstitute the powder with the appropriate diluent before use.

Benefits

• Broad-spectrum antibacterial activity
• Effective against various bacterial pathogens
• Suitable for severe infections
• Convenient once-daily dosing (for some indications)
• Good tissue penetration
• Well-established safety profile for antibiotics

Side Effects

• Diarrhea
• Nausea
• Vomiting
• Rash
• Injection site pain
• Headache
• Dizziness
• Eosinophilia
• Thrombocytosis
• Leukopenia
• Elevated liver enzymes
• Allergic reactions (e.g., anaphylaxis)

Safety Measures

• Alcohol - Avoid alcohol during treatment and for several days after, as some cephalosporins can cause a disulfiram-like reaction (nausea, vomiting, flushing, headache).
• Pregnancy - Generally considered safe for use during pregnancy, especially in the second and third trimesters. Consult a doctor for specific advice.
• Breastfeeding - Small amounts may pass into breast milk. Generally considered compatible with breastfeeding, but monitor the infant for diarrhea or thrush.
• Liver - Use with caution in patients with severe liver impairment, as dosage adjustments may be necessary. Liver function should be monitored.
• Kidney - Dosage adjustments may be required in patients with severe renal impairment. Close monitoring of kidney function is advisable.
• Lung - Effective in treating bacterial lung infections. No specific contraindications related to underlying non-infectious lung conditions.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.