CETANIL M 50 10'S

About

CETANIL M 50 is a combination medication primarily used in the management of essential hypertension. It typically combines a dihydropyridine calcium channel blocker (like Cilnidipine) with a beta-adrenergic blocking agent (like Metoprolol). The calcium channel blocker component works by relaxing blood vessels, thereby reducing peripheral vascular resistance and lowering blood pressure. It also helps to improve blood flow to the heart. The beta-blocker component acts by blocking the effects of adrenaline on the heart and blood vessels, leading to a slower heart rate and reduced force of contraction, which further contributes to blood pressure reduction and can alleviate angina symptoms. This dual mechanism of action provides comprehensive control over blood pressure, especially in patients who do not achieve adequate control with monotherapy.

This combination is particularly beneficial for patients requiring more aggressive blood pressure management or those who experience reflex tachycardia with calcium channel blockers alone. It helps to mitigate some of the common side effects associated with individual agents, offering a balanced therapeutic profile. Regular monitoring of blood pressure and heart rate is essential during treatment to ensure optimal efficacy and safety.

Uses

• Management of essential hypertension.
• Treatment of angina pectoris.
• Prevention of cardiovascular events in high-risk patients.
• Adjunctive therapy for certain cardiac conditions.

Directions For Use

Take this medication orally as directed by your physician, usually once daily with or without food. Do not crush, chew, or break the tablet; swallow it whole.

Benefits

• Effective blood pressure reduction.
• Improved control of angina symptoms.
• Reduced risk of cardiovascular complications.
• Dual mechanism for comprehensive action.
• May mitigate reflex tachycardia from CCBs.
• Convenient once-daily dosing.

Side Effects

• Dizziness or lightheadedness.
• Fatigue or weakness.
• Bradycardia (slow heart rate).
• Peripheral edema (swelling of ankles/feet).
• Headache.
• Nausea or stomach upset.
• Flushing.
• Shortness of breath.
• Cold hands and feet.
• Sleep disturbances.
• Hypotension (low blood pressure).
• Muscle cramps.

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it can enhance the blood pressure-lowering effect and increase the risk of dizziness.
• Pregnancy - Consult your doctor. This medication should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
• Breastfeeding - Consult your doctor. Components may pass into breast milk; caution is advised.
• Liver - Use with caution in patients with liver impairment; dose adjustment may be necessary.
• Kidney - Use with caution in patients with kidney impairment; dose adjustment may be necessary.
• Lung - Use with caution in patients with respiratory conditions like asthma or COPD due to the beta-blocker component.

Disclaimer

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