About

Cefuroxime axetil is a well-established second-generation cephalosporin antibiotic, recognized for its broad-spectrum activity against a variety of bacterial pathogens. Its mechanism of action involves inhibiting the synthesis of the bacterial cell wall, a vital structural component, ultimately leading to the death of susceptible bacteria. As a prodrug, cefuroxime axetil is hydrolyzed in the body to its active form, cefuroxime. It demonstrates effectiveness against numerous Gram-positive and Gram-negative bacteria, including many strains that produce beta-lactamase enzymes. This antibiotic is frequently utilized in the treatment of a range of bacterial infections, such as those affecting the upper and lower respiratory tracts, urinary tract, skin, and soft tissues, as well as acute otitis media and sinusitis, offering a reliable oral treatment option.

Uses

Pharyngitis/tonsillitis
Acute bacterial otitis media
Acute bacterial sinusitis
Uncomplicated skin and skin structure infections

Directions For Use

Reconstitute the dry syrup as directed by your pharmacist. Shake the suspension well before each use. Measure the prescribed dose accurately and administer orally with food for better absorption.

Benefits

Broad-spectrum antibacterial activity
Effective against beta-lactamase producing strains
Good tissue penetration
Convenient oral dosing
Generally well-tolerated
Effective for common respiratory infections

Side Effects

Diarrhea
Nausea
Vomiting
Abdominal pain
Headache
Dizziness
Rash
Hives
Vaginal candidiasis
Oral thrush
Eosinophilia
Positive Coombs' test

Safety Measures

Alcohol - No specific interaction, but excessive alcohol may worsen gastrointestinal upset.
Pregnancy - Generally considered safe in pregnancy, but use only if clearly indicated and under medical advice.
Breastfeeding - Small amounts may pass into breast milk. Monitor the infant for potential gastrointestinal disturbances or rash. Consult a doctor.
Liver - Use with caution in patients with hepatic impairment. No specific dose adjustment is usually required, but monitoring is advisable.
Kidney - Dosage adjustment is necessary for patients with significant renal impairment. Consult your doctor for appropriate dosing.
Lung - No specific contraindications related to lung conditions. It is often used to treat respiratory tract infections.

Disclaimer

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