About

Cifomed TZ Tab is a combination antibiotic and anti-protozoal medication, typically containing Ciprofloxacin and Tinidazole. Ciprofloxacin is a broad-spectrum fluoroquinolone antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria. It works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, repair, and recombination, leading to bacterial cell death. Tinidazole is an anti-protozoal and antibacterial agent that is effective against various anaerobic bacteria and protozoa. It functions by damaging the DNA of susceptible organisms, thereby inhibiting their growth and survival.

This combination therapy is particularly useful in treating mixed infections where both aerobic and anaerobic bacteria, as well as protozoa, may be involved. Such infections commonly occur in the gastrointestinal tract, gynecological system, and in cases of surgical prophylaxis. The synergistic action of Ciprofloxacin and Tinidazole provides comprehensive coverage, making it an effective choice for complex infections that might not respond to a single agent. It is crucial to complete the full course of treatment to prevent the development of antibiotic resistance.

Uses

Treatment of mixed bacterial infections.
Management of gastrointestinal infections.
Treatment of gynecological infections.
Prophylaxis in certain surgical procedures.

Directions For Use

Take as directed by your physician, usually with food to reduce gastrointestinal discomfort. Do not skip doses.

Benefits

Broad-spectrum antimicrobial activity.
Effective against bacteria and protozoa.
Treats mixed infections comprehensively.
Reduces risk of treatment failure.
Targets both aerobic and anaerobic pathogens.
Offers synergistic therapeutic effects.

Side Effects

Nausea
Vomiting
Diarrhea
Abdominal pain
Dizziness
Headache
Metallic taste
Rash
Photosensitivity
Tendonitis/Tendon rupture (rare)
Peripheral neuropathy (rare)
QT prolongation (rare)

Safety Measures

Alcohol - Avoid alcohol during treatment and for at least 72 hours after the last dose of Tinidazole, due to potential disulfiram-like reactions.
Pregnancy - Generally not recommended during pregnancy due to potential risks to the fetus. Consult a doctor for alternatives.
Breastfeeding - Not recommended during breastfeeding as both components pass into breast milk and may harm the infant.
Liver - Use with caution in patients with liver impairment; dosage adjustment may be necessary.
Kidney - Use with caution in patients with kidney impairment; dosage adjustment is usually required.
Lung - Use with caution in patients with a history of myasthenia gravis, as fluoroquinolones can exacerbate muscle weakness.

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