CRESTOR 5 MG 30'S

About

Rosuvastatin is a highly effective HMG-CoA reductase inhibitor, commonly known as a statin, prescribed for the management of elevated cholesterol levels and the prevention of cardiovascular disease. It functions by competitively inhibiting the enzyme HMG-CoA reductase, which is a rate-limiting step in cholesterol biosynthesis within the liver. This inhibition leads to a substantial reduction in low-density lipoprotein cholesterol (LDL-C), often referred to as "bad" cholesterol, as well as total cholesterol and triglycerides. Concurrently, rosuvastatin can modestly increase high-density lipoprotein cholesterol (HDL-C), or "good" cholesterol.

Through its comprehensive lipid-modifying effects, rosuvastatin significantly reduces the risk of major cardiovascular events such as myocardial infarction, stroke, and the need for arterial revascularization. Its potent action and established safety profile position it as a cornerstone therapy in the primary and secondary prevention strategies for individuals with dyslipidemia and high cardiovascular risk.

Uses

• Treatment of primary hypercholesterolemia and mixed dyslipidemia.
• Reduction of elevated LDL-C, total cholesterol, and triglycerides.
• Prevention of major cardiovascular events in patients at high risk.
• Treatment of homozygous familial hypercholesterolemia.

Directions For Use

Take orally once daily, with or without food, at any time of day, as prescribed by your doctor.

Benefits

• Significantly lowers LDL ("bad") cholesterol.
• Reduces total cholesterol and triglycerides.
• Increases HDL ("good") cholesterol.
• Decreases risk of heart attack and stroke.
• Slows progression of atherosclerosis.
• Effective in various forms of hyperlipidemia.

Side Effects

• Muscle pain (myalgia)
• Headache
• Nausea
• Abdominal pain
• Weakness (asthenia)
• Constipation
• Dizziness
• Increased liver enzymes (transaminases)
• Diabetes mellitus (new onset)
• Memory loss or confusion (rare)
• Rhabdomyolysis (very rare, severe muscle breakdown)
• Kidney failure (secondary to rhabdomyolysis)

Safety Measures

• Alcohol - Excessive alcohol intake can increase the risk of liver problems; use with caution.
• Pregnancy - Contraindicated during pregnancy due to potential fetal harm; use effective contraception.
• Breastfeeding - Contraindicated during breastfeeding as it may pass into breast milk and harm the infant.
• Liver - Contraindicated in active liver disease or unexplained persistent elevations of serum transaminases.
• Kidney - Use with caution in severe renal impairment; dose adjustment may be necessary.
• Lung - No specific contraindications, but interstitial lung disease has been reported rarely with statins.

Disclaimer

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