About
This medication is a fixed-dose combination therapy designed to manage two critical cardiovascular risk factors: hypertension and dyslipidemia. It comprises Amlodipine, a long-acting dihydropyridine calcium channel blocker, and Rosuvastatin, a potent HMG-CoA reductase inhibitor. Amlodipine exerts its antihypertensive effect by relaxing the smooth muscles in the walls of blood vessels, leading to peripheral vasodilation and a subsequent reduction in blood pressure. Rosuvastatin works by inhibiting the enzyme responsible for cholesterol synthesis in the liver, thereby significantly lowering levels of low-density lipoprotein (LDL-C), total cholesterol, and triglycerides, while also increasing high-density lipoprotein (HDL-C). This synergistic combination provides comprehensive cardiovascular protection, effectively controlling blood pressure and improving lipid profiles in patients who require both antihypertensive and lipid-lowering treatment, simplifying their medication regimen and enhancing adherence.
Uses
- Treatment of essential hypertension
- Management of primary hypercholesterolemia
- Treatment of mixed dyslipidemia
- Prevention of major cardiovascular events
Directions For Use
Take one tablet orally once daily, with or without food, as prescribed by your doctor.
Benefits
- Effectively lowers high blood pressure
- Reduces LDL ("bad") cholesterol
- Increases HDL ("good") cholesterol
- Decreases the risk of heart attack and stroke
- Simplifies medication regimen
- Provides comprehensive cardiovascular protection
Side Effects
- Headache
- Dizziness
- Peripheral edema (swelling)
- Flushing
- Fatigue
- Nausea
- Abdominal pain
- Muscle pain (myalgia)
- Constipation
- Palpitations
- Increased blood sugar levels
- Liver enzyme elevations
Safety Measures
- Alcohol - Alcohol may potentiate the hypotensive effect of amlodipine and increase the risk of rosuvastatin-induced liver toxicity. Avoid excessive intake.
- Pregnancy - Contraindicated during pregnancy due to the risk of fetal harm, particularly from rosuvastatin.
- Breastfeeding - Not recommended for use during breastfeeding as both active ingredients may be excreted in breast milk.
- Liver - Use with caution in patients with hepatic impairment; contraindicated in active liver disease.
- Kidney - Rosuvastatin dose adjustment may be needed in severe renal impairment. Amlodipine is generally safe.
- Lung - Generally considered safe for patients with lung conditions; no specific precautions are usually required.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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| Shop Location | Assam, India |
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