About
This medication is a fixed-dose combination therapy designed to manage two critical cardiovascular risk factors: hypertension and dyslipidemia. It comprises Amlodipine, a long-acting dihydropyridine calcium channel blocker, and Rosuvastatin, a potent HMG-CoA reductase inhibitor. Amlodipine exerts its antihypertensive effect by relaxing the smooth muscles in the walls of blood vessels, leading to peripheral vasodilation and a subsequent reduction in blood pressure. Rosuvastatin works by inhibiting the enzyme responsible for cholesterol synthesis in the liver, thereby significantly lowering levels of low-density lipoprotein (LDL-C), total cholesterol, and triglycerides, while also increasing high-density lipoprotein (HDL-C). This synergistic combination provides comprehensive cardiovascular protection, effectively controlling blood pressure and improving lipid profiles in patients who require both antihypertensive and lipid-lowering treatment, simplifying their medication regimen and enhancing adherence.
Uses
- Treatment of essential hypertension
- Management of primary hypercholesterolemia
- Treatment of mixed dyslipidemia
- Prevention of cardiovascular events in high-risk patients
Directions For Use
Take one tablet orally once daily, with or without food, or as directed by your healthcare provider.
Benefits
- Effectively lowers high blood pressure
- Significantly reduces LDL ("bad") cholesterol
- Decreases the risk of heart attack and stroke
- Improves overall cardiovascular health
- Offers convenient once-daily dosing
- Manages two conditions with one medication
Side Effects
- Headache
- Dizziness
- Swelling in ankles/feet (edema)
- Flushing
- Fatigue
- Nausea
- Abdominal pain
- Muscle pain (myalgia)
- Constipation
- Palpitations
- Increased blood sugar levels
- Liver enzyme elevations
Safety Measures
- Alcohol - Alcohol may enhance the blood pressure-lowering effect of amlodipine and increase the risk of liver issues with rosuvastatin. Use with caution.
- Pregnancy - Contraindicated in pregnancy due to potential fetal harm from rosuvastatin and possible effects from amlodipine.
- Breastfeeding - Not recommended during breastfeeding as both components may pass into breast milk.
- Liver - Use with caution in patients with liver impairment; contraindicated in active liver disease.
- Kidney - Rosuvastatin dose adjustment may be needed in severe renal impairment. Amlodipine is generally safe.
- Lung - Generally safe for use in patients with lung conditions; no specific contraindications.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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| Shop Location | Assam, India |
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