DEFCORT TM TAB

About

DEFCORT TM TAB contains Deflazacort, a synthetic glucocorticoid with potent anti-inflammatory and immunosuppressive properties. It is a corticosteroid prodrug that is converted to its active metabolite in the body. Deflazacort works by binding to glucocorticoid receptors, modulating gene expression to suppress the immune response and reduce inflammation. It is often preferred over other corticosteroids due to its potentially lower impact on bone mineral density and glucose metabolism at equivalent anti-inflammatory doses. This makes it a valuable option for long-term management of various inflammatory and autoimmune conditions, as well as in specific muscular dystrophies.

Uses

• Treatment of inflammatory conditions
• Management of autoimmune diseases
• Alleviation of severe allergic reactions
• Therapy for Duchenne muscular dystrophy

Directions For Use

Take orally with food to minimize gastrointestinal upset, as directed by your physician. Do not stop abruptly.

Benefits

• Potent anti-inflammatory action
• Effective immunosuppressant
• Alleviates symptoms of allergic reactions
• Manages flares in autoimmune diseases
• May have less impact on bone density than other steroids
• Improves muscle strength in Duchenne muscular dystrophy

Side Effects

• Weight gain
• Increased appetite
• Mood changes (irritability, anxiety)
• Insomnia
• Fluid retention
• High blood pressure
• Increased blood sugar levels
• Osteoporosis (long-term use)
• Cataracts
• Glaucoma
• Increased risk of infection
• Adrenal suppression

Safety Measures

• Alcohol - Avoid excessive alcohol consumption as it can increase the risk of gastrointestinal irritation and other side effects associated with corticosteroids.
• Pregnancy - Consult your doctor. Deflazacort should be used during pregnancy only if the potential benefits justify the potential risk to the fetus.
• Breastfeeding - Consult your doctor. Deflazacort is excreted into breast milk; monitor the infant for any adverse effects.
• Liver - Use with caution in patients with severe liver disease, as dose adjustment may be necessary due to altered metabolism.
• Kidney - Generally safe for use in patients with kidney conditions; no major dose adjustments are typically required.
• Lung - Use with caution in patients with active lung infections, such as tuberculosis, as corticosteroids can suppress the immune response.

Disclaimer

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