About
Doxotero 50mg Injection is an anti-cancer medication used in the treatment of various cancers. Cancer is a condition where cells grow abnormally and divide uncontrollably. Doxotero 50mg is primarily used as adjuvant chemotherapy in women with breast cancer involving axillary lymph nodes following surgical resection. It is also effective in treating neuroblastoma—a cancer that originates in nerve cells and mainly affects children—and Wilms' tumor, a type of kidney cancer seen in children.
This injection contains Doxorubicin, a drug that belongs to the anthracycline topoisomerase inhibitors class. It works by intercalating between DNA base pairs and inhibiting the topoisomerase II enzyme, leading to the uncoiling of the DNA double helix. This action disrupts DNA and RNA synthesis, ultimately killing cancer cells.
Common side effects of Doxotero 50mg may include nausea, headache, abdominal pain, loss of appetite, vomiting, dizziness, mouth sores, fatigue, back pain, red-colored urine, diarrhea, and pain at the injection site. Most of these side effects are temporary and do not require medical attention. However, if they persist or worsen, consult your doctor. The injection must be administered by a qualified healthcare professional, so do not attempt to self-administer. The dosage will be determined by your doctor based on your individual health condition.
Avoid Doxotero 50mg Injection if you are allergic to Doxorubicin or any of its components. It is contraindicated in patients with severe heart failure, recent myocardial infarction (MI), significant drug-induced bone marrow suppression, or severe liver impairment. Inform your doctor if you have any cardiovascular issues, liver or kidney disease, or are taking CYP3A4 or CYP2D6 inducers, as these may lead to serious interactions or side effects.
Since Doxotero 50mg Injection is known to cause embryo-fetal toxicity, it should not be used during pregnancy or breastfeeding. Inform your doctor if you are pregnant, planning to become pregnant, or currently breastfeeding before beginning treatment.
Uses
- Breast cancer
- Lung cancer
- Malignant lymphomas
- Certain types of leukemia
Directions for use
This medicine should be administered by a doctor or nurse. Please do not attempt to self-administer it.
Side effects
Serious:
- Low white blood cell count
- Severe allergic reaction (shortness of breath, dizziness, itchy rash, tightness in chest or throat)
- Decreased activity in the bone marrow
- Increase the level of liver enzyme
Common:
- Lack of appetite
- Nausea, vomiting
- Diarrhea
- Hair loss
- Swelling in the mouth and ankle
- Numbness, pain, tingling, swelling, or reddening in the palms and feet
- Weight gain
- Arrhythmia (irregular heartbeats)
- Red or watery eyes, excess tear production
Safety Measures
Alcohol - The safety of consuming alcohol while receiving Doxotero 50mg Injection is not known. Please consult your doctor for appropriate guidance.
Pregnancy -Doxotero 50mg Injection may cause harm to an unborn baby. Inform your doctor if you are pregnant or planning to become pregnant before starting this medication.
Breastfeeding - Discontinue breastfeeding before beginning treatment with Doxotero 50mg Injection, as its active ingredient may pass into breast milk and potentially harm your baby. Inform your doctor if you are currently breastfeeding before starting this medication.
Liver - Inform your doctor if you have any liver conditions before receiving Doxotero 50mg Injection, as this medication is not recommended for patients with severe liver disorders. Dose adjustments may be necessary based on your liver function.
Kidney - If you have a current or past history of kidney disease, inform your doctor. Depending on your condition, they may adjust the dosage or recommend an appropriate alternative treatment.
Disclaimer
Med E Hub is committed to delivering reliable, expert-reviewed information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment.
Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
Our goal is to complement, not replace, the essential doctor-patient relationship.
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