-17%

DUPHASTON 10MG TAB 10 'S

Salt Composition: Dydrogesterone (10mg)  
Manufacturer: Abbott  
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About

Dydrogesterone is a synthetic progestogen structurally similar to natural progesterone, designed to mimic its actions in the body. It is orally active and selectively acts on the uterus, inducing a full secretory endometrium in an estrogen-primed uterus, which is crucial for successful implantation and maintenance of pregnancy. Unlike some other progestogens, dydrogesterone does not possess estrogenic, androgenic, anabolic, or corticosteroid activity, minimizing potential side effects related to these hormonal actions. Its primary role is to correct progesterone deficiencies, thereby supporting various physiological processes dependent on adequate progesterone levels, such as regulating menstrual cycles and preventing miscarriage. This makes it a valuable therapeutic agent in conditions where endogenous progesterone production is insufficient or requires supplementation. It is well-absorbed after oral administration, reaching peak plasma concentrations rapidly, and is primarily metabolized in the liver, with metabolites excreted mainly via urine.

Uses

  • Treatment of endometriosis
  • Management of dysfunctional uterine bleeding
  • Support in assisted reproductive technologies (ART)
  • Prevention of recurrent miscarriage due to progesterone deficiency

Directions For Use

Take as directed by your physician, usually with water. Dosage and duration depend on the specific condition being treated.

Benefits

  • Supports healthy uterine lining
  • Helps regulate menstrual cycles
  • Reduces symptoms of endometriosis
  • Assists in maintaining pregnancy
  • Low androgenic side effects
  • Orally active and well-tolerated

Side Effects

  • Headache
  • Nausea
  • Abdominal pain
  • Breast tenderness
  • Dizziness
  • Fatigue
  • Weight gain
  • Skin reactions (rash, itching)
  • Menstrual irregularities
  • Vaginal bleeding/spotting
  • Depressed mood
  • Fluid retention

Safety Measures

  • Alcohol - Moderate alcohol consumption is generally not contraindicated, but excessive intake may exacerbate some side effects or liver metabolism.
  • Pregnancy - Often used to support pregnancy in cases of progesterone deficiency; however, use should be strictly under medical supervision.
  • Breastfeeding - Dydrogesterone is excreted in breast milk; therefore, its use during breastfeeding is generally not recommended.
  • Liver - Use with caution in patients with a history of liver disease or impaired liver function, as it is metabolized in the liver.
  • Kidney - No specific dose adjustment is typically required for patients with kidney impairment, but caution is advised in severe cases.
  • Lung - Generally considered safe for use in patients with lung conditions; no specific precautions are usually necessary.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.

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