About
Dutasteride and Tamsulosin combination therapy is a well-established treatment for men experiencing moderate to severe symptoms of benign prostatic hyperplasia (BPH) and an enlarged prostate. Dutasteride, a dual 5-alpha reductase inhibitor, works by reducing the production of dihydrotestosterone (DHT), a key hormone responsible for prostate growth. This action leads to a significant reduction in prostate volume over time, addressing the underlying cause of BPH.
Tamsulosin, an alpha-1 adrenergic antagonist, provides rapid symptomatic relief by relaxing the smooth muscles in the prostate and bladder neck, thereby improving urine flow and reducing obstructive urinary symptoms. The synergistic effect of these two agents offers superior symptom improvement and a greater reduction in the risk of BPH progression and related complications compared to monotherapy.
Uses
- Treatment of symptomatic benign prostatic hyperplasia (BPH).
- Improvement of urinary flow in men with enlarged prostate.
- Reduction of the risk of acute urinary retention.
- Decrease the likelihood of BPH-related surgery.
Directions For Use
Take orally as directed by your physician, usually once daily after a meal. Do not crush or chew the capsule.
Benefits
- Significantly improves urinary flow.
- Reduces prostate gland size over time.
- Alleviates bothersome BPH symptoms.
- Decreases the risk of BPH progression.
- Lowers the incidence of acute urinary retention.
- Offers a comprehensive approach to BPH management.
Side Effects
- Dizziness
- Ejaculation disorder
- Decreased libido
- Breast tenderness
- Breast enlargement
- Orthostatic hypotension
- Nasal congestion
- Headache
- Nausea
- Diarrhea
- Allergic reactions (rare)
- Impotence
Safety Measures
- Alcohol - Alcohol may increase the risk of dizziness and orthostatic hypotension when taken with this medication. Use with caution.
- Pregnancy - This medication is contraindicated in women, especially pregnant women, due to the risk of fetal abnormalities.
- Breastfeeding - Not applicable as this medication is for male use.
- Liver - Use with caution in patients with liver impairment; dose adjustment may be necessary.
- Kidney - Generally safe for use in patients with kidney conditions; no dose adjustment typically required.
- Lung - No specific contraindications or precautions related to lung conditions are generally noted.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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