About
Pirfenidone is an antifibrotic agent specifically indicated for the treatment of idiopathic pulmonary fibrosis (IPF), a debilitating and ultimately fatal chronic lung disease characterized by progressive scarring and irreversible loss of lung function. While its precise mechanism of action is not fully elucidated, pirfenidone is believed to exert its therapeutic effects through multiple pathways. It inhibits the synthesis of pro-fibrotic cytokines such as transforming growth factor-beta (TGF-β) and tumor necrosis factor-alpha (TNF-α), which are key mediators in the fibrotic process. By reducing the proliferation of fibroblasts and the production of collagen and other extracellular matrix proteins, pirfenidone helps to slow the progression of fibrosis, preserve lung function, and reduce the decline in forced vital capacity (FVC) in patients with IPF.
Uses
- Treatment of idiopathic pulmonary fibrosis (IPF).
- Slows the decline in lung function in IPF.
- Reduces disease progression in IPF patients.
- Improves progression-free survival in IPF.
Directions For Use
Take orally with food to reduce nausea, as directed by your doctor. Swallow the tablets whole with water.
Benefits
- Slows the progression of idiopathic pulmonary fibrosis.
- Helps preserve lung function over time.
- Reduces the risk of acute exacerbations of IPF.
- Improves survival rates in IPF patients.
- Offers a targeted treatment for a severe lung disease.
- Can improve quality of life for IPF patients.
Side Effects
- Nausea
- Diarrhea
- Dyspepsia
- Abdominal pain
- Fatigue
- Headache
- Dizziness
- Insomnia
- Photosensitivity reaction
- Rash
- Anorexia
- Liver enzyme elevation
Safety Measures
- Alcohol - Avoid or limit alcohol consumption due to increased risk of liver toxicity.
- Pregnancy - Not recommended during pregnancy due to potential risks; use effective contraception.
- Breastfeeding - Not recommended during breastfeeding as it is unknown if it passes into breast milk.
- Liver - Contraindicated in severe liver impairment; use with caution and monitor liver function in mild to moderate impairment.
- Kidney - Use with caution in severe kidney impairment; dose adjustment may be necessary.
- Lung - Specifically used for lung fibrosis; however, monitor for new or worsening respiratory symptoms.
Disclaimer
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| Shop Location | Assam, India |
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