About
EMVOID is an antiemetic medication, specifically an oral neurokinin-1 (NK1) receptor antagonist, meticulously designed to prevent chemotherapy-induced nausea and vomiting (CINV). Its therapeutic action stems from its ability to selectively block the NK1 receptors located in the brain, particularly in the area postrema. These receptors are activated by substance P, a neuropeptide that plays a pivotal role in mediating the emetic reflex. By inhibiting the binding of substance P to its receptors, EMVOID effectively prevents both the acute phase (within 24 hours) and the delayed phase (24-120 hours) of CINV, which are common and often debilitating side effects of many chemotherapy regimens. It is typically used in combination with other classes of antiemetics, such as corticosteroids (e.g., dexamethasone) and 5-HT3 receptor antagonists (e.g., ondansetron), to provide comprehensive and synergistic protection against nausea and vomiting, thereby significantly improving patient comfort, adherence to treatment, and overall quality of life during cancer therapy.
Uses
- Prevention of acute CINV from highly emetogenic chemotherapy.
- Prevention of delayed CINV from highly emetogenic chemotherapy.
- Prevention of CINV from moderately emetogenic chemotherapy.
- Used in combination with other antiemetics.
Directions For Use
Take orally as directed by your doctor, typically starting before chemotherapy and continuing for a few days after.
Benefits
- Highly effective in preventing CINV.
- Covers both acute and delayed phases of CINV.
- Significantly improves patient comfort.
- Reduces the incidence and severity of nausea and vomiting.
- Can be used with various chemotherapy regimens.
- Enhances overall quality of life during treatment.
Side Effects
- Fatigue and asthenia
- Hiccups
- Constipation
- Diarrhea
- Headache
- Dyspepsia (indigestion)
- Dizziness
- Anorexia (loss of appetite)
- Neutropenia (low white blood cell count)
- Elevated liver enzymes
- Bradycardia (slow heart rate)
- Abdominal pain
Safety Measures
- Alcohol - No specific contraindication, but moderation is advised; discuss with your doctor.
- Pregnancy - Use only if clearly needed and potential benefits outweigh risks; consult your doctor.
- Breastfeeding - Not recommended during breastfeeding as the drug may be excreted in breast milk.
- Liver - Use with caution in patients with severe hepatic impairment; monitor liver function.
- Kidney - No dose adjustment is typically needed for patients with renal impairment.
- Lung - No specific lung-related safety concerns are commonly associated with this medication.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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