Estroz 25mg Tablet

About

Estroz 25mg Tablet contains Exemestane, an irreversible steroidal aromatase inactivator used in the treatment of hormone-receptor-positive breast cancer in postmenopausal women. It works by permanently binding to and inactivating the aromatase enzyme, which is responsible for converting androgens into estrogens in peripheral tissues. By significantly reducing estrogen levels, Exemestane effectively deprives estrogen-dependent breast cancer cells of the growth stimulus, thereby inhibiting tumor progression and recurrence.

This targeted therapy is a crucial option for patients whose breast cancer is sensitive to hormonal influences, particularly after initial endocrine therapies like tamoxifen. It is well-absorbed orally and metabolized in the liver. While generally effective, patients should be monitored for potential side effects, including bone mineral density changes and cardiovascular risks. Its role in adjuvant and metastatic settings has significantly improved outcomes for postmenopausal breast cancer patients.

Uses

• Adjuvant treatment of early breast cancer
• Advanced breast cancer after tamoxifen failure
• Hormone-receptor-positive breast cancer
• Postmenopausal women with breast cancer

Directions For Use

Take one tablet orally once daily after a meal. Follow your doctor's instructions precisely.

Benefits

• Effective in hormone-receptor-positive breast cancer
• Reduces the risk of breast cancer recurrence
• Improves disease-free survival in postmenopausal women
• Provides irreversible aromatase inhibition
• Well-tolerated in many patients
• Convenient oral administration

Side Effects

• Hot flashes
• Joint pain (arthralgia)
• Fatigue
• Headache
• Nausea
• Insomnia
• Increased sweating
• Bone loss (osteoporosis)
• Vaginal dryness
• Hair thinning
• Depression
• Peripheral edema

Safety Measures

• Alcohol - No specific contraindication, but excessive alcohol may worsen hot flashes or fatigue.
• Pregnancy - Contraindicated during pregnancy as it can cause fetal harm. Use effective contraception.
• Breastfeeding - Not recommended during breastfeeding as the drug may pass into breast milk and harm the infant.
• Liver - Use with caution; dosage adjustment may be necessary in patients with severe hepatic impairment.
• Kidney - Use with caution; dosage adjustment may be necessary in patients with severe renal impairment.
• Lung - No specific lung-related contraindications for this medication.

Disclaimer

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