FPSTATIN 40 10'S

About

Fluvastatin is a synthetic lipid-lowering agent belonging to the class of HMG-CoA reductase inhibitors, commonly known as statins. It works by competitively inhibiting HMG-CoA reductase, an enzyme critical in the liver for cholesterol synthesis. This inhibition leads to a reduction in intracellular cholesterol, which in turn upregulates LDL receptors on hepatocyte surfaces, increasing the clearance of low-density lipoprotein (LDL) cholesterol from the bloodstream. Fluvastatin is primarily used to reduce elevated total cholesterol, LDL-C, and triglycerides, and to increase high-density lipoprotein (HDL) cholesterol in patients with primary hypercholesterolemia and mixed dyslipidemia.

It also plays a role in preventing cardiovascular events in high-risk individuals by stabilizing atherosclerotic plaques and improving endothelial function. Fluvastatin is an effective adjunct to diet for reducing elevated apolipoprotein B (ApoB) and is considered a foundational therapy for managing dyslipidemia and reducing cardiovascular risk.

Uses

• Reduction of elevated total cholesterol and LDL-C in primary hypercholesterolemia.
• Treatment of mixed dyslipidemia to lower triglycerides and raise HDL-C.
• Prevention of cardiovascular events in patients with coronary heart disease.
• Adjunct to diet for reducing elevated apolipoprotein B (ApoB).

Directions For Use

Take once daily in the evening, with or without food, as directed by your physician.

Benefits

• Effectively lowers LDL ("bad") cholesterol levels.
• Reduces triglyceride levels.
• Increases HDL ("good") cholesterol levels.
• Decreases the risk of heart attack and stroke.
• Slows the progression of atherosclerosis.
• Improves overall cardiovascular health.

Side Effects

• Headache
• Nausea
• Diarrhea
• Abdominal pain
• Muscle pain (myalgia)
• Fatigue
• Insomnia
• Rash
• Elevated liver enzymes (transaminases)
• Increased creatine kinase (CK) levels
• Arthralgia (joint pain)
• Dizziness

Safety Measures

• Alcohol - Excessive alcohol consumption can increase the risk of liver problems associated with statin use. Limit alcohol intake.
• Pregnancy - Fluvastatin is contraindicated during pregnancy due to the potential for fetal harm. Effective contraception should be used by women of childbearing potential.
• Breastfeeding - Fluvastatin is contraindicated during breastfeeding as it may be excreted in breast milk and could harm the infant.
• Liver - Contraindicated in active liver disease or unexplained persistent elevations of serum transaminases. Liver function tests should be monitored.
• Kidney - No dose adjustment is typically required for mild to moderate renal impairment. Use with caution in severe renal impairment.
• Lung - While rare, interstitial lung disease has been reported with statins. Monitor for symptoms like dyspnea, cough, and fever.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.