About
Gemer 4 contains Glimepiride, an oral sulfonylurea medication used to lower blood glucose levels in adults with type 2 diabetes mellitus. Glimepiride works primarily by stimulating the beta cells in the pancreas to release more insulin. This increased insulin secretion helps to move glucose from the bloodstream into cells, thereby reducing blood glucose levels. It also has some extrapancreatic effects, such as increasing peripheral glucose uptake and utilization.
This medication is typically used as an adjunct to diet and exercise, either as monotherapy or in combination with other antidiabetic agents like metformin. Due to its mechanism of action, glimepiride can cause hypoglycemia, especially if meals are delayed, skipped, or if there is insufficient carbohydrate intake. Regular monitoring of blood glucose levels is essential to prevent and manage hypoglycemia.
Uses
- To improve glycemic control in adults with type 2 diabetes mellitus.
- As an adjunct to diet and exercise.
- As monotherapy when diet and exercise alone are insufficient.
- In combination with metformin or insulin when single agents are inadequate.
Directions For Use
Take orally once daily with breakfast or the first main meal of the day, as directed by your physician.
Benefits
- Effectively lowers blood glucose levels.
- Convenient once-daily dosing.
- Can be used alone or in combination.
- Well-established efficacy in diabetes management.
- Helps achieve target HbA1c levels.
- Relatively affordable treatment option.
Side Effects
- Hypoglycemia (low blood sugar)
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Headache
- Dizziness
- Allergic skin reactions (rash, itching)
- Weight gain
- Liver enzyme elevations (rare)
- Blood dyscrasias (e.g., leukopenia, thrombocytopenia, rare)
- Hyponatremia (rare)
Safety Measures
- Alcohol - Avoid excessive alcohol intake as it can potentiate hypoglycemia and may cause a disulfiram-like reaction.
- Pregnancy - Not recommended during pregnancy due to potential for fetal hypoglycemia; insulin is generally preferred.
- Breastfeeding - Not recommended during breastfeeding as sulfonylureas can pass into breast milk and may cause infant hypoglycemia.
- Liver - Use with caution in liver impairment; dose adjustments may be necessary, and liver function should be monitored.
- Kidney - Use with caution in kidney impairment; dose adjustments are often required to reduce the risk of hypoglycemia.
- Lung - Generally safe for use in patients with lung conditions; no specific contraindications.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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