GLUCORYL M1 FORTE 15S

About

Glucoryl M1 Forte is a combination oral hypoglycemic agent indicated for the treatment of type 2 diabetes mellitus in adults. It combines glimepiride, a sulfonylurea that stimulates insulin secretion from pancreatic beta cells, and metformin, a biguanide that reduces hepatic glucose production and improves insulin sensitivity in peripheral tissues. This synergistic action helps to achieve better glycemic control than either drug used alone. The "Forte" variant indicates a higher dosage strength, suitable for patients who require more intensive management of their blood sugar levels when diet, exercise, and lower-dose monotherapy or combination therapy have proven insufficient. It aims to normalize blood glucose levels, thereby reducing the risk of long-term complications associated with uncontrolled diabetes, such as cardiovascular disease and kidney damage.

Uses

• Management of type 2 diabetes.
• When diet and exercise are insufficient.
• As an adjunct to lifestyle modifications.
• To improve glycemic control.

Directions For Use

Take as prescribed by your doctor, usually with meals. Swallow the tablet whole with water.

Benefits

• Effectively lowers blood glucose levels.
• Improves insulin sensitivity.
• Reduces glucose production by the liver.
• Helps prevent long-term diabetes complications.
• Provides dual mechanism of action for better control.
• Convenient fixed-dose combination.

Side Effects

• Hypoglycemia
• Nausea
• Diarrhea
• Abdominal pain
• Headache
• Dizziness
• Metallic taste
• Weight gain
• Skin rash
• Lactic acidosis (rare)
• Vitamin B12 deficiency
• Flatulence

Safety Measures

• Alcohol - Avoid or limit alcohol consumption due to increased risk of hypoglycemia and lactic acidosis.
• Pregnancy - Generally not recommended during pregnancy; consult your doctor for safer alternatives.
• Breastfeeding - Not advised during breastfeeding as components may pass into breast milk.
• Liver - Use with caution in patients with liver impairment; increased risk of lactic acidosis and hypoglycemia.
• Kidney - Contraindicated in severe renal impairment; dose adjustment required for moderate impairment.
• Lung - Use with caution in severe respiratory conditions due to potential for lactic acidosis.

Disclaimer

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