GLUCORYL M1 15 S

About

Glucoryl M1 is an oral antidiabetic medication used for the management of type 2 diabetes mellitus in adults. It combines glimepiride, a sulfonylurea that stimulates insulin release from pancreatic beta cells, and metformin, a biguanide that reduces glucose production by the liver and improves insulin sensitivity. This combination therapy is particularly effective for patients whose blood sugar levels are not adequately controlled by diet, exercise, or monotherapy with either glimepiride or metformin. By targeting different pathways involved in glucose regulation, Glucoryl M1 helps to achieve and maintain optimal glycemic control, thereby reducing the risk of long-term diabetes complications such as cardiovascular events, neuropathy, and nephropathy. It provides a comprehensive approach to managing blood glucose, improving the body's natural response to insulin and reducing glucose output.

Uses

• Treatment of type 2 diabetes.
• As an adjunct to diet and exercise.
• When monotherapy is insufficient.
• To improve blood sugar control.

Directions For Use

Take orally, usually with meals, as prescribed by your physician. Do not chew or crush the tablet.

Benefits

• Lowers both fasting and post-meal blood glucose.
• Enhances the body's sensitivity to insulin.
• Reduces glucose output from the liver.
• Helps prevent the progression of diabetes complications.
• Provides a comprehensive approach to glycemic management.
• Convenient fixed-dose combination.

Side Effects

• Hypoglycemia
• Nausea
• Diarrhea
• Stomach upset
• Headache
• Dizziness
• Metallic taste
• Weight gain
• Skin rash
• Lactic acidosis (rare)
• Vitamin B12 deficiency
• Flatulence

Safety Measures

• Alcohol - Avoid or limit alcohol intake to minimize the risk of hypoglycemia and lactic acidosis.
• Pregnancy - Not recommended during pregnancy; consult your doctor for alternative treatments.
• Breastfeeding - Avoid use while breastfeeding as components may be excreted in breast milk.
• Liver - Use with caution in patients with hepatic impairment; monitor liver function closely.
• Kidney - Contraindicated in severe renal dysfunction; dose adjustment necessary for moderate impairment.
• Lung - Exercise caution in severe respiratory conditions due to the risk of lactic acidosis.

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