GLYCINOROM OD 60 10

About

GLYCINOROM OD 60 contains Gliclazide 60mg, a modified-release sulfonylurea medication used for the effective management of type 2 diabetes mellitus. Gliclazide acts primarily by stimulating the pancreatic beta cells to secrete insulin, particularly in response to elevated blood glucose levels. This mechanism helps to lower blood sugar. The "OD" (Once Daily) formulation ensures a prolonged and steady release of the active ingredient, providing sustained glycemic control throughout the 24-hour period, which can contribute to better patient adherence and reduced fluctuations in blood glucose.

This medication is indicated for adults with type 2 diabetes when dietary management, physical exercise, and weight reduction alone are insufficient to achieve adequate glycemic control. It is crucial that patients understand the importance of consistent meal timing and carbohydrate intake to minimize the risk of hypoglycemia, which is a potential side effect of insulin secretagogues. Regular monitoring of blood glucose and HbA1c levels is vital to assess treatment efficacy and safety.

Uses

• Treatment of type 2 diabetes mellitus
• Reduction of high blood glucose levels
• Enhancement of insulin secretion
• Adjunct to diet and exercise programs

Directions For Use

Take one tablet orally once daily with breakfast, as prescribed by your doctor. Swallow the tablet whole; do not crush, chew, or break it.

Benefits

• Effective once-daily dosing
• Provides sustained glycemic control
• Significantly lowers HbA1c
• Helps improve pancreatic beta-cell function
• Reduces post-prandial glucose excursions
• Well-established safety and efficacy profile

Side Effects

• Hypoglycemia (low blood sugar)
• Weight gain
• Nausea
• Diarrhea
• Constipation
• Abdominal discomfort
• Headache
• Dizziness
• Skin rash
• Pruritus (itching)
• Urticaria (hives)
• Elevated liver enzymes (rare)

Safety Measures

• Alcohol - Avoid alcohol consumption as it can potentiate the hypoglycemic effect of Gliclazide and may cause a disulfiram-like reaction.
• Pregnancy - Not recommended during pregnancy. Insulin is generally the preferred treatment for diabetes in pregnant women.
• Breastfeeding - Not recommended during breastfeeding due to the potential for Gliclazide to pass into breast milk and cause hypoglycemia in the infant.
• Liver - Use with caution in patients with liver impairment; dose adjustment may be necessary to prevent drug accumulation and severe hypoglycemia.
• Kidney - Use with caution in patients with kidney impairment; dose adjustment may be necessary to reduce the risk of drug accumulation and hypoglycemia.
• Lung - Generally not a primary concern for lung conditions. However, severe respiratory insufficiency could indirectly impact glucose regulation.

Disclaimer

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