About
HER Tinib 250mg Tablet is an oral antineoplastic agent belonging to the class of tyrosine kinase inhibitors (TKIs). This medication is designed to selectively target and inhibit specific protein kinases that are crucial for the growth and proliferation of cancer cells. By blocking these aberrant signaling pathways, HER Tinib effectively interferes with tumor cell survival, angiogenesis, and metastasis, leading to a reduction in tumor size and progression. Its mechanism of action is highly specific, aiming to minimize damage to healthy cells compared to traditional chemotherapy.
The therapeutic efficacy of HER Tinib is primarily observed in various solid tumors where these specific kinase pathways are overactive or mutated. It represents a significant advancement in targeted cancer therapy, offering a more personalized approach to treatment. Clinical studies have demonstrated its ability to improve progression-free survival and overall response rates in eligible patient populations, providing a valuable option for managing advanced or metastatic cancers. Careful patient selection based on biomarker testing is often crucial to optimize treatment outcomes and minimize potential adverse effects.
Uses
- Treatment of specific types of non-small cell lung cancer.
- Management of advanced renal cell carcinoma.
- Therapy for gastrointestinal stromal tumors (GIST).
- Treatment of certain forms of chronic myeloid leukemia.
Directions For Use
Take orally once daily with or without food, as directed by your oncologist. Do not crush, chew, or split the tablet.
Benefits
- Targets specific cancer cell growth pathways.
- Offers a personalized approach to cancer treatment.
- Can improve progression-free survival in eligible patients.
- Available as a convenient oral tablet.
- May reduce tumor burden and inhibit metastasis.
- Potentially fewer systemic side effects compared to conventional chemotherapy.
Side Effects
- Fatigue.
- Nausea.
- Diarrhea.
- Skin rash.
- Edema (swelling).
- Hypertension (high blood pressure).
- Myelosuppression (low blood counts).
- Liver enzyme elevation.
- Headache.
- Muscle pain (myalgia).
- Stomatitis (mouth sores).
- Hand-foot syndrome.
Safety Measures
- Alcohol - Avoid or limit alcohol consumption as it may exacerbate certain side effects like liver toxicity or gastrointestinal upset.
- Pregnancy - Contraindicated during pregnancy due to potential fetal harm. Effective contraception must be used by patients of reproductive potential.
- Breastfeeding - Not recommended during breastfeeding as the drug may be excreted in breast milk and could harm the infant.
- Liver - Use with caution in patients with hepatic impairment. Dose adjustments may be necessary, and liver function should be closely monitored.
- Kidney - Use with caution in patients with renal impairment. Dose adjustments may be necessary, and kidney function should be closely monitored.
- Lung - Monitor for signs of interstitial lung disease (ILD) or pneumonitis, which can be serious adverse events. Discontinue if ILD is confirmed.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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