LEVERA 750

About

LEVERA 750 contains Levetiracetam, an antiepileptic drug primarily used in the management of various seizure types. Its precise mechanism of action is not fully understood but is believed to involve binding to the synaptic vesicle protein 2A (SV2A) in the brain, which modulates neurotransmitter release and helps to stabilize neuronal hyperexcitability. This action contributes to its broad-spectrum efficacy against different forms of epilepsy.

Levetiracetam is effective as both monotherapy and adjunctive therapy for partial-onset seizures, myoclonic seizures in patients with juvenile myoclonic epilepsy, and primary generalized tonic-clonic seizures. It is characterized by a favorable pharmacokinetic profile, including rapid absorption, linear kinetics, and minimal protein binding, which contributes to a low potential for drug-drug interactions. Its renal excretion pathway means dose adjustments are necessary in patients with impaired kidney function.

Uses

• Adjunctive therapy for partial-onset seizures with or without secondary generalization.
• Monotherapy for partial-onset seizures in newly diagnosed epilepsy patients.
• Adjunctive therapy for myoclonic seizures in patients with juvenile myoclonic epilepsy.
• Adjunctive therapy for primary generalized tonic-clonic seizures.

Directions For Use

Take orally with or without food, as directed by your physician. Do not crush or chew the tablets.

Benefits

• Effective in controlling various types of seizures.
• Generally well-tolerated with a favorable side effect profile.
• Minimal drug-drug interaction potential.
• Can be used as monotherapy or adjunctive therapy.
• Rapid onset of action.
• Improves quality of life for epilepsy patients.

Side Effects

• Drowsiness
• Dizziness
• Weakness
• Infection (nasopharyngitis)
• Headache
• Irritability
• Aggression
• Nausea
• Diarrhea
• Loss of appetite
• Tremor
• Coordination problems

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it can increase central nervous system depression and exacerbate side effects like dizziness and drowsiness.
• Pregnancy - Consult your doctor. Levetiracetam should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
• Breastfeeding - Levetiracetam is excreted into human milk. Monitor breastfed infants for potential adverse effects such as sedation or irritability.
• Liver - Generally, no dose adjustment is required for patients with mild to moderate liver impairment. Use with caution in severe cases.
• Kidney - Dose adjustment is necessary for patients with impaired renal function, as the drug is primarily excreted by the kidneys.
• Lung - No specific direct adverse effects on lung function are commonly associated with Levetiracetam.

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