About
This medication combines Methylcobalamin, an active coenzyme form of Vitamin B12, with Nortriptyline, a tricyclic antidepressant (TCA). Methylcobalamin is essential for the health and regeneration of nerve cells, playing a critical role in the synthesis of myelin, the protective sheath that insulates nerve fibers and ensures efficient nerve signal transmission. Its presence is vital for repairing damaged nerves and maintaining overall neurological function. Nortriptyline primarily acts by inhibiting the reuptake of norepinephrine and, to a lesser extent, serotonin in the central nervous system. This increase in neurotransmitter availability helps to modulate pain pathways, particularly in chronic neuropathic pain conditions, and can also contribute to mood stabilization. The synergistic effect of this combination aims to both alleviate the symptoms of nerve pain, such as burning, tingling, and numbness, and support the physiological recovery and maintenance of nerve health, providing comprehensive relief for patients.
Uses
- Treatment of neuropathic pain.
- Management of diabetic neuropathy.
- Relief from post-herpetic neuralgia.
- Adjunctive therapy for chronic pain syndromes.
Directions For Use
Take this medication orally, usually once daily at bedtime, as directed by your physician.
Benefits
- Reduces nerve pain and discomfort.
- Promotes nerve regeneration and health.
- Improves sleep patterns.
- Alleviates burning and tingling sensations.
- Stabilizes mood in chronic pain conditions.
- Supports myelin sheath formation.
Side Effects
- Drowsiness
- Dry mouth
- Constipation
- Blurred vision
- Dizziness
- Urinary retention
- Weight gain
- Orthostatic hypotension
- Increased heart rate
- Nausea
- Headache
- Difficulty concentrating
Safety Measures
- Alcohol - Avoid alcohol as it can significantly enhance the sedative effects and other CNS side effects.
- Pregnancy - Consult your doctor; Nortriptyline should be used only if clearly needed and the benefit outweighs the risk.
- Breastfeeding - Nortriptyline passes into breast milk; discuss with your doctor before breastfeeding.
- Liver - Use with caution in patients with liver impairment; dose adjustment may be necessary for Nortriptyline.
- Kidney - Use with caution in patients with kidney impairment; dose adjustment may be necessary for Nortriptyline.
- Lung - Generally safe for lung conditions, but caution with severe respiratory depression due to sedative effects.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
Our goal is to complement, not replace, the essential doctor-patient relationship.
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| Shop Location | Assam, India |

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