Megte 160mg Tablet

About

Megte 160mg Tablet is a synthetic progestin, primarily utilized for its significant appetite-stimulating and anti-cachectic effects in patients experiencing profound and often debilitating weight loss, a condition known as cachexia, which is commonly associated with chronic illnesses such as advanced cancer or acquired immunodeficiency syndrome (AIDS). While the precise mechanism by which it stimulates appetite is not fully elucidated, it is believed to involve complex modulation of various metabolic pathways, including cytokine production, and direct effects on the hypothalamic centers that regulate appetite. Beyond its role in weight management, it also possesses antineoplastic properties, making it a valuable agent in the palliative treatment of certain hormone-dependent cancers. This specific, higher dosage is particularly tailored for effectively managing severe cachexia and anorexia.

Uses

• Anorexia and cachexia in AIDS patients
• Significant weight loss in cancer patients
• Palliative treatment of advanced breast cancer
• Palliative treatment of advanced endometrial cancer

Directions For Use

Take one tablet orally once daily, or as directed by your healthcare provider.

Benefits

• Increases appetite and food intake
• Promotes weight gain in cachectic patients
• Improves quality of life in advanced illness
• May reduce nausea associated with illness
• Offers palliative relief in certain cancers
• Well-tolerated for its intended use

Side Effects

• Weight gain
• Nausea
• Diarrhea
• Flatulence
• Rash
• Insomnia
• Hot flashes
• Headache
• Edema
• Thromboembolic events (rare)
• Adrenal suppression (long-term, high dose)
• Breakthrough bleeding (in women)

Safety Measures

• Alcohol - Moderate alcohol consumption is generally safe, but excessive intake may exacerbate some side effects like nausea or dizziness.
• Pregnancy - Contraindicated during pregnancy due to potential harm to the fetus; use effective contraception.
• Breastfeeding - Not recommended during breastfeeding as it may be excreted in milk and affect the infant.
• Liver - Use with caution in patients with liver impairment; monitor liver function periodically.
• Kidney - Generally safe for use in patients with kidney conditions; no dose adjustment typically required.
• Lung - No specific contraindications related to lung conditions, but monitor for thromboembolic events, especially in predisposed patients.

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