MIGRABETA TR-20 10

About

MIGRABETA TR-20 contains Metoprolol, an extended-release beta-blocker primarily utilized for the comprehensive management of various cardiovascular conditions and as an effective prophylaxis for migraine headaches. The "TR" (extended-release) formulation is crucial as it ensures a gradual and sustained release of the medication into the bloodstream, thereby providing consistent therapeutic effects over a full 24-hour period. Metoprolol exerts its action by selectively blocking beta-adrenergic receptors, which leads to a reduction in heart rate, cardiac output, and systemic blood pressure. In the context of migraine prophylaxis, it helps to stabilize the blood vessels in the brain, significantly reducing the frequency and severity of migraine attacks, thus improving the patient's quality of life.

Uses

• Prophylaxis of migraine headaches.
• Treatment of essential hypertension.
• Management of angina pectoris.
• Adjunctive therapy in stable symptomatic heart failure.

Directions For Use

Take one tablet orally once daily, preferably with food, or as directed by your physician. Do not crush or chew.

Benefits

• Effectively reduces frequency and severity of migraine attacks.
• Lowers high blood pressure.
• Relieves symptoms of angina.
• Provides sustained therapeutic effect over 24 hours.
• Reduces heart rate and workload on the heart.
• Improves quality of life for migraine sufferers.

Side Effects

• Fatigue
• Dizziness
• Bradycardia (slow heart rate)
• Hypotension
• Nausea
• Diarrhea
• Shortness of breath (especially in susceptible patients)
• Cold hands and feet
• Insomnia or vivid dreams
• Depression
• Bronchospasm (rare)
• Masking of hypoglycemia symptoms

Safety Measures

• Alcohol - Avoid excessive alcohol as it can increase dizziness and drowsiness, and may enhance the blood pressure-lowering effect.
• Pregnancy - Use only if clearly needed and potential benefits outweigh risks. Monitor neonate for bradycardia and hypoglycemia.
• Breastfeeding - Generally considered safe, but monitor infant for signs of beta-blockade. Consult a healthcare professional.
• Liver - Use with caution in patients with severe liver impairment; dose adjustment may be necessary due to reduced metabolism.
• Kidney - Generally safe for use in patients with kidney conditions; no significant dose adjustment usually required.
• Lung - Contraindicated in severe asthma or bronchospasm. Use with extreme caution in other obstructive lung diseases.

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