PALMIGES

About

PALMIGES is a powerful combination medication formulated to provide effective relief from moderate to severe pain and inflammation. It integrates Paracetamol, a widely recognized analgesic and antipyretic, which primarily exerts its effects in the central nervous system to reduce pain perception and fever. Its exact mechanism involves inhibition of prostaglandin synthesis, though it differs from NSAIDs in its peripheral action. The second component, Diclofenac, is a potent non-steroidal anti-inflammatory drug (NSAID) that works by inhibiting both COX-1 and COX-2 enzymes, thereby significantly reducing the production of prostaglandins responsible for inflammation, pain, and fever at the site of injury or disease. This dual-action approach offers synergistic benefits, providing comprehensive pain management and reducing inflammatory responses associated with various musculoskeletal conditions, post-operative pain, and other inflammatory disorders, leading to improved comfort and functional recovery.

Uses

• Osteoarthritis
• Rheumatoid arthritis
• Ankylosing spondylitis
• Dental pain
• Post-operative pain
• Acute musculoskeletal pain

Directions For Use

Take one tablet orally two to three times daily, preferably after food, or as advised by your doctor.

Benefits

• Dual action pain relief
• Reduces inflammation and swelling
• Effective for various pain types
• Controls fever
• Improves mobility
• Faster symptom resolution

Side Effects

• Nausea
• Vomiting
• Abdominal pain
• Diarrhea
• Heartburn
• Indigestion
• Dizziness
• Headache
• Rash
• Liver enzyme elevation
• Gastric ulcers (with prolonged use)
• Fluid retention

Safety Measures

• Alcohol - Avoid alcohol; it significantly increases the risk of liver damage (paracetamol) and gastrointestinal bleeding (diclofenac).
• Pregnancy - Not recommended, especially in the third trimester due to diclofenac; consult your doctor.
• Breastfeeding - Not recommended; components may pass into breast milk and affect the infant.
• Liver - Use with extreme caution in hepatic impairment; regular monitoring of liver function is crucial.
• Kidney - Use with caution in renal impairment; diclofenac can impair kidney function.
• Lung - Use with caution in asthmatic patients as NSAIDs can precipitate bronchospasm.

Disclaimer

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