About
Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) widely used for its analgesic, anti-inflammatory, and antipyretic properties. The sustained-release (SR) formulation of 75mg is designed to provide prolonged therapeutic effects, allowing for less frequent dosing and improved patient compliance. It works by inhibiting cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2, which are responsible for the synthesis of prostaglandins. Prostaglandins are lipid compounds that mediate inflammation, pain, and fever in the body. By reducing prostaglandin production, diclofenac effectively alleviates symptoms associated with various inflammatory conditions. This mechanism of action makes it a cornerstone in the management of chronic pain and inflammatory disorders, offering significant relief to patients and improving their quality of life.
Uses
- Relief of pain and inflammation in osteoarthritis.
- Management of rheumatoid arthritis symptoms.
- Treatment of ankylosing spondylitis.
- Alleviation of acute musculoskeletal pain.
Directions For Use
Take one tablet orally, usually once daily, with food or milk to minimize gastrointestinal upset. Do not crush or chew the tablet.
Benefits
- Effective pain relief.
- Reduces inflammation.
- Long-lasting action due to sustained release.
- Improves joint mobility.
- Reduces fever.
- Convenient once-daily dosing.
Side Effects
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Indigestion
- Heartburn
- Headache
- Dizziness
- Rash
- Fluid retention
- Increased blood pressure
- Liver enzyme elevation
Safety Measures
- Alcohol - Avoid or limit alcohol consumption as it may increase the risk of gastrointestinal bleeding and liver damage when taken with diclofenac.
- Pregnancy - Generally not recommended in the third trimester due to potential fetal cardiovascular effects; use in early pregnancy only if clearly needed and benefits outweigh risks.
- Breastfeeding - Small amounts may pass into breast milk; use with caution and monitor the infant for adverse effects, or consider alternative medications.
- Liver - Use with caution in patients with liver impairment; regular monitoring of liver function tests is advised.
- Kidney - Use with caution in patients with kidney impairment as NSAIDs can worsen renal function; dose adjustment may be necessary.
- Lung - Use with caution in asthmatic patients, as NSAIDs can precipitate bronchospasm in susceptible individuals.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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