PENOGAB-M 10

About

PENOGAB-M 10 is a combination medication specifically formulated for the effective management of neuropathic pain. It typically combines Pregabalin, an anticonvulsant that binds to the alpha-2-delta subunit of voltage-gated calcium channels, thereby reducing the release of various neurotransmitters involved in pain signaling. This action helps to calm overactive nerve cells responsible for neuropathic symptoms. The formulation also includes Methylcobalamin, an active form of Vitamin B12, which is crucial for nerve health, myelin sheath formation, and nerve regeneration. This synergistic approach targets both the symptomatic relief of nerve pain and the underlying nerve health, providing comprehensive care for conditions like diabetic neuropathy, post-herpetic neuralgia, and other forms of chronic nerve pain, ultimately improving patient comfort and functional capacity.

Uses

• Treatment of neuropathic pain conditions.
• Management of diabetic neuropathy.
• Relief from post-herpetic neuralgia.
• Support for nerve regeneration and health.

Directions For Use

Take one capsule daily, or as directed by your physician, preferably at bedtime. Swallow the capsule whole with water.

Benefits

• Effectively reduces neuropathic pain intensity.
• Supports nerve health and regeneration.
• Alleviates burning, tingling, and numbness.
• Improves sleep quality in chronic pain patients.
• Offers a dual-action approach to pain relief.
• Enhances overall patient comfort and functional capacity.

Side Effects

• Dizziness
• Drowsiness
• Peripheral edema
• Weight gain
• Blurred vision
• Dry mouth
• Constipation
• Ataxia
• Headache
• Nausea
• Fatigue
• Difficulty concentrating

Safety Measures

• Alcohol - Avoid alcohol consumption as it can significantly enhance the central nervous system depressant effects of Pregabalin, leading to increased drowsiness and impaired coordination.
• Pregnancy - Consult a doctor. Use only if the potential benefit outweighs the risk to the fetus, as Pregabalin has shown teratogenic effects in animal studies.
• Breastfeeding - Consult a doctor. Pregabalin passes into breast milk; monitor the infant for sedation or poor feeding.
• Liver - Generally safe, as Pregabalin is minimally metabolized by the liver. Methylcobalamin is also generally safe.
• Kidney - Pregabalin dosage requires significant adjustment in patients with kidney impairment. Use with caution and monitor renal function closely.
• Lung - Caution is advised in patients with severe respiratory depression or sleep apnea due to potential for CNS depressant effects from Pregabalin.

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