Proapaci 60mg Tablet 120's

About

Proapaci 60mg Tablet is an oral antiplatelet medication belonging to the class of P2Y12 platelet aggregation inhibitors. It works by selectively and reversibly binding to the P2Y12 receptor on platelets, preventing adenosine diphosphate (ADP)-mediated platelet activation and aggregation. This mechanism reduces the formation of blood clots, which can lead to serious cardiovascular events. Its rapid onset of action and potent antiplatelet effects make it a crucial component in the management of acute coronary syndromes (ACS) and in patients undergoing percutaneous coronary intervention (PCI).

The drug is metabolized primarily in the liver and excreted via the bile and urine. Its pharmacokinetic profile supports twice-daily dosing to maintain consistent antiplatelet efficacy. Clinical studies have demonstrated its superiority over other antiplatelet agents in reducing the incidence of cardiovascular death, myocardial infarction, and stroke in high-risk patients, while carefully balancing the risk of bleeding.

Uses

• Prevention of thrombotic events in acute coronary syndromes (ACS).
• Reduction of cardiovascular death, myocardial infarction, and stroke.
• Adjunct therapy following percutaneous coronary intervention (PCI).
• Prevention of stent thrombosis after coronary stenting.

Directions For Use

Take orally, usually twice daily, with or without food, as directed by your physician. Do not crush or chew the tablet.

Benefits

• Significantly reduces risk of major adverse cardiovascular events.
• Rapid onset of antiplatelet action.
• Effective in patients with acute coronary syndromes.
• Reduces incidence of stent thrombosis.
• Improved outcomes post-percutaneous coronary intervention.
• Offers potent and reversible platelet inhibition.

Side Effects

• Bleeding (e.g., bruising, nosebleeds, gastrointestinal bleeding)
• Dyspnea (shortness of breath)
• Headache
• Nausea
• Diarrhea
• Dizziness
• Bradycardia (slow heart rate)
• Hypotension (low blood pressure)
• Rash
• Increased uric acid levels
• Gout
• Syncope (fainting)

Safety Measures

• Alcohol - Concurrent alcohol use may increase the risk of gastrointestinal bleeding. Use with caution and in moderation.
• Pregnancy - Generally not recommended during pregnancy due to potential fetal harm and increased bleeding risk. Consult a doctor.
• Breastfeeding - Excretion into breast milk is unknown; therefore, breastfeeding is generally not advised. Seek medical advice.
• Liver - Use with caution in patients with moderate liver impairment; contraindicated in severe liver disease.
• Kidney - No dose adjustment typically required for mild to moderate renal impairment; use with caution in severe impairment.
• Lung - May exacerbate or cause dyspnea; use with caution in patients with pre-existing respiratory conditions like asthma or COPD.

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