About
RIFGUARD 400 MG TABS contain Rifaximin, a unique, non-systemic antibiotic primarily active within the gastrointestinal tract. Its mechanism involves inhibiting bacterial RNA synthesis, thereby preventing the growth and replication of susceptible bacteria in the gut. A key characteristic of Rifaximin is its extremely low systemic absorption, meaning that less than 0.4% of the orally administered dose enters the bloodstream. This localized action minimizes the risk of systemic side effects and reduces the potential for widespread antibiotic resistance, making it a targeted therapy for gut-related conditions.
The drug is effective against a broad spectrum of gut bacteria, including both aerobic and anaerobic gram-positive and gram-negative organisms. It is particularly valuable in managing conditions where an imbalance or overgrowth of gut bacteria contributes to symptoms. This includes treating acute infectious diarrhea, preventing recurrence of hepatic encephalopathy by reducing ammonia-producing bacteria, and alleviating symptoms of irritable bowel syndrome with diarrhea (IBS-D) by modulating the gut microbiome. Its safety profile and targeted action make it a preferred choice for these specific indications.
Uses
- Traveler's diarrhea caused by non-invasive E. coli
- Hepatic encephalopathy (reduction of recurrence)
- Irritable bowel syndrome with diarrhea (IBS-D)
- Small intestinal bacterial overgrowth (SIBO)
Directions For Use
Take orally as prescribed by your doctor, usually with or without food.
Benefits
- Targeted action within the gastrointestinal tract
- Minimal systemic absorption, reducing systemic side effects
- Effective for acute infectious diarrhea
- Helps manage chronic gut conditions like IBS-D
- Reduces ammonia production in hepatic encephalopathy
- Generally well-tolerated with a favorable safety profile
Side Effects
- Nausea
- Abdominal pain
- Flatulence
- Headache
- Dizziness
- Fatigue
- Constipation
- Diarrhea
- Peripheral edema
- Muscle spasms
- Rash
- Pruritus
Safety Measures
- Alcohol - Avoid or limit alcohol consumption, especially if you have underlying liver conditions, as it can exacerbate them.
- Pregnancy - Use with caution; consult a doctor before use to assess potential risks and benefits.
- Breastfeeding - Exercise caution; consult a healthcare provider as it is unknown if Rifaximin is excreted in human milk.
- Liver - Beneficial for hepatic encephalopathy; generally safe for liver conditions, but monitor patients with severe hepatic impairment.
- Kidney - No dose adjustment is typically required for renal impairment due to minimal systemic absorption.
- Lung - No specific lung-related precautions; generally safe for patients with lung conditions.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
Our goal is to complement, not replace, the essential doctor-patient relationship.
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| Shop Location | Assam, India |

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