ROSUFIT 20MG TAB

About

Rosuvastatin is a potent synthetic HMG-CoA reductase inhibitor, commonly known as a statin. It works by competitively inhibiting the enzyme HMG-CoA reductase, which is responsible for the rate-limiting step in cholesterol biosynthesis in the liver. This action leads to a significant reduction in low-density lipoprotein cholesterol (LDL-C), total cholesterol, and triglycerides, while also increasing high-density lipoprotein cholesterol (HDL-C). Its primary role is in the management of various forms of dyslipidemia, including primary hypercholesterolemia and mixed dyslipidemia, where elevated lipid levels pose a significant cardiovascular risk. Furthermore, rosuvastatin is crucial in the primary and secondary prevention of major cardiovascular events such as myocardial infarction and stroke, particularly in individuals identified as high-risk due to existing atherosclerotic disease or multiple risk factors. Regular use helps to stabilize atherosclerotic plaques and improve endothelial function, contributing to overall cardiovascular health.

Uses

• Primary hypercholesterolemia and mixed dyslipidemia.
• Homozygous familial hypercholesterolemia.
• Prevention of major cardiovascular events in high-risk individuals.
• Atherosclerotic cardiovascular disease.

Directions For Use

Take orally once daily, with or without food, as directed by your physician. Do not crush or chew the tablet.

Benefits

• Significantly lowers LDL-C and total cholesterol.
• Reduces triglyceride levels.
• Increases beneficial HDL-C.
• Decreases the risk of heart attack and stroke.
• Slows the progression of atherosclerosis.
• Improves overall cardiovascular health.

Side Effects

• Muscle pain (myalgia)
• Headache
• Nausea
• Abdominal pain
• Weakness (asthenia)
• Dizziness
• Constipation
• Diarrhea
• Joint pain (arthralgia)
• Increased blood sugar levels
• Elevated liver enzymes
• Rash

Safety Measures

• Alcohol - Limit alcohol intake as it may increase the risk of liver problems and muscle side effects when taken with rosuvastatin.
• Pregnancy - Rosuvastatin is contraindicated in pregnancy due to potential fetal harm. Use effective contraception.
• Breastfeeding - Not recommended during breastfeeding as it may pass into breast milk and harm the infant.
• Liver - Use with caution in patients with a history of liver disease; regular liver function tests are advised. Contraindicated in active liver disease.
• Kidney - Dosage adjustment may be necessary in severe renal impairment. Use with caution.
• Lung - Generally safe for use in patients with lung conditions; no specific contraindications related to lung health.

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