STATPURE A 10/75 MG TAB

About

STATPURE A 10/75 MG TAB is a combination medication containing Atorvastatin 10mg and Aspirin 75mg. Atorvastatin is an HMG-CoA reductase inhibitor (statin) that effectively lowers elevated levels of LDL-C (bad cholesterol), total cholesterol, and triglycerides, while also increasing HDL-C (good cholesterol). It achieves this by inhibiting the enzyme responsible for cholesterol synthesis in the liver. Aspirin, an antiplatelet agent, works by irreversibly inhibiting cyclooxygenase-1 (COX-1), which prevents the formation of thromboxane A2, a potent inducer of platelet aggregation.

This combination is primarily indicated for the secondary prevention of cardiovascular events in patients who have established atherosclerotic cardiovascular disease, such as a history of myocardial infarction, stroke, or peripheral arterial disease. It provides both lipid-lowering benefits and antiplatelet effects, addressing two critical aspects of cardiovascular risk management. The 10mg dose of Atorvastatin is suitable for initial therapy or for patients requiring moderate cholesterol reduction, while the 75mg Aspirin dose provides effective antiplatelet aggregation to prevent thrombotic events.

Uses

• Secondary prevention of cardiovascular events.
• Management after myocardial infarction or stroke.
• Reduction of cardiovascular risk in high-risk patients.
• For patients with established atherosclerotic disease.

Directions For Use

Take orally once daily, preferably at the same time each day, with or without food, as directed by your physician. Do not crush or chew the tablets.

Benefits

• Reduces LDL-C and total cholesterol effectively.
• Prevents platelet aggregation and clot formation.
• Significantly lowers the risk of heart attack and stroke.
• Provides dual action for comprehensive cardiovascular protection.
• Convenient single-tablet regimen.
• Improves long-term cardiovascular outcomes.

Side Effects

• Headache
• Nausea
• Dyspepsia
• Abdominal pain
• Muscle pain (myalgia)
• Increased liver enzymes
• Bleeding (e.g., bruising, nosebleeds)
• Diarrhea
• Fatigue
• Rash
• Dizziness
• Tinnitus (with high aspirin doses)

Safety Measures

• Alcohol - Limit alcohol intake as it can increase the risk of liver problems with atorvastatin and gastrointestinal bleeding with aspirin.
• Pregnancy - Contraindicated due to potential fetal harm; women of childbearing potential should use effective contraception.
• Breastfeeding - Not recommended as components may pass into breast milk, potentially affecting the infant.
• Liver - Contraindicated in active liver disease or unexplained persistent elevations of serum transaminases; use with caution in patients with a history of liver disease.
• Kidney - Use with caution in severe renal impairment; aspirin may worsen kidney function in some cases.
• Lung - Use with caution in patients with asthma or aspirin-induced respiratory disease due to potential bronchospasm.

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