Taxhal 100mg Injection

About

Taxhal 100mg Injection is a standard-dose taxane-based chemotherapy agent, administered intravenously for the treatment of various malignancies. Its mechanism of action involves stabilizing microtubules by binding to tubulin, thereby preventing their depolymerization. This disruption of the dynamic equilibrium of the microtubule system is critical for cell division and other cellular functions. By arresting cancer cells in the G2/M phase of the cell cycle, Taxhal inhibits cell proliferation and induces apoptosis. This cytotoxic effect makes it a valuable therapeutic option, often used alone or in combination with other agents, to manage and control tumor growth.

Uses

• Treatment of breast cancer
• Management of ovarian cancer
• Therapy for non-small cell lung cancer
• Used in certain gastric cancers

Directions For Use

Administered intravenously by a medical professional. The dosage and treatment schedule are determined by the treating physician based on the specific cancer and patient factors.

Benefits

• Effective against a range of solid tumors
• Inhibits cancer cell proliferation
• Induces tumor regression and control
• Improves patient outcomes and survival
• Can be used in neoadjuvant or adjuvant settings
• Well-characterized safety and efficacy profile

Side Effects

• Myelosuppression (low blood cell counts)
• Peripheral neuropathy (nerve damage)
• Alopecia (hair loss)
• Nausea and vomiting
• Fatigue and weakness
• Fluid retention (edema)
• Hypersensitivity reactions (allergic reactions)
• Mucositis (mouth sores)
• Arthralgia (joint pain) and myalgia (muscle pain)
• Diarrhea
• Skin rash
• Increased risk of infection

Safety Measures

• Alcohol - Advised to avoid or limit alcohol intake due to potential for increased gastrointestinal upset and liver strain.
• Pregnancy - Contraindicated. Known to cause fetal harm. Effective contraception is essential during treatment and for a period thereafter.
• Breastfeeding - Not recommended. The drug may pass into breast milk and could harm the nursing infant.
• Liver - Use with caution; dose adjustments may be required in patients with hepatic impairment to reduce the risk of increased systemic exposure and toxicity.
• Kidney - Monitor renal function. While primarily metabolized by the liver, caution is advised in severe renal dysfunction.
• Lung - Patients should be monitored for signs of pulmonary toxicity, such as new or worsening cough or dyspnea, particularly those with pre-existing lung conditions.

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