About
Cefixime is a third-generation cephalosporin antibiotic, effective against a wide range of Gram-positive and Gram-negative bacteria. It exerts its bactericidal action by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. This dispersible tablet formulation is commonly prescribed for various bacterial infections, offering a convenient treatment option, especially for pediatric patients or those with difficulty swallowing. Its broad spectrum makes it a valuable agent in empirical therapy, helping to resolve infections and prevent complications.
Uses
- Treatment of uncomplicated urinary tract infections.
- Management of acute otitis media.
- Therapy for pharyngitis and tonsillitis.
- Treatment of acute exacerbations of chronic bronchitis.
Directions For Use
Disperse the tablet in a small amount of water before administration. Take orally as directed by your doctor, usually once daily, with or without food. Complete the full prescribed course.
Benefits
- Broad-spectrum antibacterial activity.
- Effective against common respiratory pathogens.
- Convenient once-daily dosing for many indications.
- Dispersible formulation for ease of administration, especially for children.
- Helps prevent infection complications.
- Generally well-tolerated by most patients.
- Available in oral form for ease of administration.
Side Effects
- Diarrhea
- Nausea
- Vomiting
- Abdominal pain
- Headache
- Dizziness
- Skin rash
- Allergic reactions (e.g., itching, hives)
- Superinfection (e.g., oral thrush, vaginal yeast infection)
- Changes in blood counts (e.g., eosinophilia)
- Elevated liver enzymes (transient)
- Flatulence
Safety Measures
- Alcohol - It is generally advisable to limit alcohol consumption while taking Cefixime, as it may exacerbate gastrointestinal side effects like nausea or dizziness.
- Pregnancy - Cefixime is generally considered safe for use during pregnancy (Category B), but it should only be used if clearly needed and under medical supervision.
- Breastfeeding - Small amounts of Cefixime may pass into breast milk. While generally considered safe, monitor the infant for potential gastrointestinal disturbances like diarrhea or thrush.
- Liver - Use Cefixime with caution in patients with severe liver impairment. No specific dose adjustment is typically required, but close monitoring is advised.
- Kidney - Dose adjustment is necessary for patients with moderate to severe renal impairment (creatinine clearance < 60 mL/min) to prevent accumulation and potential toxicity.
- Lung - No specific contraindications related to primary lung conditions. Cefixime is often used to treat bacterial lung infections.
Disclaimer
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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.
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