TEBINA 250 TAB

About

Terbinafine is an allylamine antifungal agent primarily used to treat dermatophyte infections of the skin, hair, and nails. It works by inhibiting squalene epoxidase, an enzyme involved in fungal ergosterol synthesis. This leads to an accumulation of squalene within the fungal cell, which is toxic and disrupts cell membrane function, ultimately leading to fungal cell death.

Oral terbinafine is particularly effective for onychomycosis (fungal nail infections) due to its ability to concentrate in the nail bed and maintain therapeutic levels for an extended period after discontinuation. It is also used for severe tinea infections that are extensive or unresponsive to topical treatments, offering a systemic approach to eradicate persistent fungal pathogens.

Uses

• Treatment of onychomycosis (fungal nail infections).
• Management of tinea corporis (ringworm).
• Therapy for tinea cruris (jock itch).
• Treatment of tinea pedis (athlete's foot).

Directions For Use

Take as directed by your physician, usually once daily with or without food. Complete the full course of treatment.

Benefits

• Highly effective against dermatophytes.
• Oral formulation for systemic treatment.
• Can achieve high concentrations in skin and nails.
• Relatively short treatment courses for some conditions.
• Good safety profile for most patients.
• Available in convenient tablet form.

Side Effects

• Headache
• Nausea
• Diarrhea
• Abdominal pain
• Indigestion
• Rash
• Urticaria
• Joint pain
• Muscle pain
• Taste disturbance (dysgeusia)
• Liver enzyme elevation
• Fatigue

Safety Measures

• Alcohol - Avoid or limit alcohol consumption as it may increase the risk of liver problems, a potential side effect of terbinafine.
• Pregnancy - Generally not recommended during pregnancy unless the potential benefits outweigh the risks. Consult a doctor.
• Breastfeeding - Terbinafine passes into breast milk. Use with caution and only if clearly necessary, under medical supervision.
• Liver - Use with caution in patients with pre-existing liver disease; liver function tests may be required before and during treatment.
• Kidney - Dose adjustment may be necessary in patients with severe renal impairment. Consult a doctor.
• Lung - No specific contraindications related to lung conditions, but general caution applies for systemic medications.

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