About
Telmisartan is an angiotensin II receptor blocker (ARB) widely utilized for the effective management of essential hypertension. Its mechanism of action involves selectively blocking the AT1 receptor, thereby counteracting the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This leads to a significant reduction in peripheral vascular resistance and a subsequent lowering of blood pressure. The medication's long elimination half-life ensures sustained blood pressure control over a 24-hour period, making once-daily administration highly convenient for patients. In addition to its primary role in blood pressure regulation, Telmisartan is also indicated for the reduction of cardiovascular morbidity and mortality in adults at high risk, such as those with a history of cardiovascular disease or type 2 diabetes with evidence of end-organ damage. It helps to mitigate the risk of serious cardiovascular events like stroke and heart attack.
Uses
- Treatment of essential hypertension.
- Reduction of cardiovascular risk.
- Prevention of stroke and heart attack.
- Management of high blood pressure in adults.
Directions For Use
Take one tablet orally once daily, with or without food, as prescribed by your physician.
Benefits
- Effective in lowering blood pressure.
- Reduces risk of cardiovascular events.
- Provides 24-hour blood pressure control.
- Generally well-tolerated.
- Convenient once-daily dosing.
- Alternative for ACE inhibitor intolerant patients.
Side Effects
- Dizziness
- Headache
- Fatigue
- Hypotension
- Back pain
- Diarrhea
- Nausea
- Upper respiratory tract infection
- Cough (less common than ACE inhibitors)
- Hyperkalemia (rare)
- Angioedema (very rare)
- Syncope
Safety Measures
- Alcohol - Limit alcohol intake as it can enhance the blood pressure-lowering effect and increase dizziness.
- Pregnancy - Contraindicated during the second and third trimesters of pregnancy due to potential fetal harm.
- Breastfeeding - Not recommended; consult your doctor as it may pass into breast milk.
- Liver - Use with caution in patients with mild to moderate hepatic impairment; severe impairment is a contraindication.
- Kidney - Use with caution in patients with renal artery stenosis or severe renal impairment; monitor kidney function closely.
- Lung - Generally safe for use in patients with lung conditions.
Disclaimer
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