TERGOSIL TAB

About

TERGOSIL TAB contains Terbinafine, an antifungal agent belonging to the allylamine class. It is primarily used to treat fungal infections of the skin, hair, and nails, particularly onychomycosis (fungal nail infection) and severe tinea infections (ringworm, athlete's foot, jock itch) that are extensive or unresponsive to topical treatments. Terbinafine works by selectively inhibiting squalene epoxidase, a key enzyme in the fungal ergosterol biosynthesis pathway.

This inhibition leads to an accumulation of squalene within the fungal cell and a deficiency of ergosterol, both of which are toxic to the fungal cell, causing its death. Terbinafine is fungicidal against dermatophytes, the most common cause of skin and nail fungal infections. Its oral formulation allows for systemic distribution, reaching the site of infection in nails and hair follicles, making it highly effective for difficult-to-treat infections.

Uses

• Onychomycosis (fungal nail infections)
• Tinea corporis (ringworm)
• Tinea cruris (jock itch)
• Tinea pedis (athlete's foot)

Directions For Use

Take with or without food, as directed by your physician. Complete the full course of treatment.

Benefits

• Highly effective against dermatophytes
• Treats stubborn nail and skin fungal infections
• Fungicidal action (kills fungi)
• Systemic treatment for widespread infections
• Often leads to long-term cure
• Relieves itching and discomfort

Side Effects

• Headache
• Diarrhea
• Nausea
• Abdominal pain
• Dyspepsia
• Rash
• Taste disturbance (dysgeusia)
• Liver enzyme elevation
• Hepatotoxicity (rare, severe)
• Allergic reactions
• Neutropenia (rare)
• Dizziness

Safety Measures

• Alcohol - Avoid or limit alcohol consumption, as both alcohol and terbinafine can potentially affect liver function.
• Pregnancy - Not recommended during pregnancy unless the potential benefits outweigh the risks. Consult a doctor.
• Breastfeeding - Terbinafine is excreted in breast milk. Use is generally not recommended during breastfeeding.
• Liver - Contraindicated in patients with chronic or active liver disease. Liver function tests should be monitored.
• Kidney - Use with caution in patients with renal impairment (creatinine clearance <50 mL/min); dose reduction may be necessary.
• Lung - No specific precautions for lung conditions are typically noted, but always inform your doctor about all existing medical conditions.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.