About

TORTAXEL is a potent antineoplastic agent belonging to the taxane class of chemotherapy drugs, widely recognized for its efficacy in treating various solid tumors. Its primary mechanism of action involves disrupting the normal function of microtubules, which are dynamic components of the cellular cytoskeleton crucial for cell division, intracellular transport, and maintaining cell shape. Specifically, TORTAXEL binds to tubulin, promoting the assembly of microtubules and simultaneously inhibiting their depolymerization. This stabilization leads to the accumulation of dysfunctional and excessively stable microtubule bundles within the cell, effectively arresting cancer cells in the G2/M phase of the cell cycle. This mitotic arrest ultimately triggers programmed cell death (apoptosis), thereby inhibiting tumor growth and progression. TORTAXEL is a cornerstone in oncology, utilized either as a monotherapy or in combination with other chemotherapeutic agents, demonstrating significant clinical benefits in improving patient outcomes across a range of malignancies.

Uses

Treatment of metastatic breast cancer.
Management of non-small cell lung cancer.
Therapy for advanced prostate cancer.
Treatment of gastric adenocarcinoma.

Directions For Use

Administered intravenously by a qualified healthcare professional. Dosage and infusion schedule are determined by the patient's condition and body surface area.

Benefits

Effective against a broad spectrum of solid tumors.
Can improve overall survival in various cancer types.
Often used in combination regimens for enhanced efficacy.
Well-established clinical profile.
Available in different strengths for flexible dosing.
Contributes to disease control and symptom palliation.

Side Effects

Bone marrow suppression (neutropenia, anemia, thrombocytopenia)
Peripheral neuropathy (numbness, tingling)
Fluid retention (edema)
Hypersensitivity reactions (rash, flushing, dyspnea)
Alopecia (hair loss)
Mucositis (inflammation of mucous membranes)
Nail changes (discoloration, brittleness)
Fatigue and asthenia
Myalgia (muscle pain)
Arthralgia (joint pain)
Nausea and vomiting
Skin reactions (rash, desquamation)

Safety Measures

Alcohol - Avoid or limit alcohol consumption as it may exacerbate certain side effects or interact with the medication.
Pregnancy - Contraindicated during pregnancy due to potential for fetal harm; effective contraception is required.
Breastfeeding - Not recommended during breastfeeding as the drug may be excreted in breast milk and harm the infant.
Liver - Use with caution and potential dose adjustment in patients with hepatic impairment due to increased risk of toxicity.
Kidney - Administer with caution in patients with renal impairment; monitor kidney function closely during treatment.
Lung - Rarely associated with interstitial lung disease; monitor for new or worsening respiratory symptoms.

Disclaimer

MedEHub is committed to delivering reliable, expert-reviewd information to help consumers make informed health decisions. However, the content provided on this website is for informational purposes only and is not intended to replace professional medical advice, diagnosis or treatment.

Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.

Shipping & Location