VILDAGARD M 50/500 15'S

About

VILDAGARD M 50/500 is a combination medication containing Vildagliptin (50mg) and Metformin (500mg), prescribed for adults with type 2 diabetes mellitus to improve glycemic control. Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that enhances the body's natural ability to lower high blood glucose levels by increasing insulin release from the pancreas and decreasing glucagon levels, particularly after meals. Metformin, a biguanide, works by reducing glucose production in the liver and improving insulin sensitivity in peripheral tissues, allowing the body to use insulin more effectively.

This dual-action approach provides comprehensive blood sugar management, addressing both insulin secretion and insulin resistance. It is typically used when diet and exercise alone, or monotherapy with either component, are insufficient to achieve adequate blood glucose control, helping to reduce HbA1c levels and prevent diabetes-related complications.

Uses

• Treatment of type 2 diabetes mellitus.
• Improving blood sugar control.
• Used when diet and exercise are inadequate.
• As an add-on therapy to other antidiabetic agents.

Directions For Use

Take orally with meals, usually once or twice daily, as prescribed by your doctor.

Benefits

• Dual mechanism for effective glucose control.
• Reduces both fasting and post-meal glucose.
• Low risk of hypoglycemia compared to sulfonylureas.
• May lead to modest weight loss (metformin).
• Improves insulin sensitivity and pancreatic function.
• Convenient fixed-dose combination therapy.

Side Effects

• Nausea
• Diarrhea
• Abdominal pain
• Headache
• Dizziness
• Nasopharyngitis
• Tremor
• Fatigue
• Hypoglycemia (less common)
• Lactic acidosis (rare, metformin)
• Vitamin B12 deficiency (metformin)
• Pancreatitis (rare, vildagliptin)

Safety Measures

• Alcohol - Avoid excessive alcohol intake due to increased risk of lactic acidosis with metformin.
• Pregnancy - Not recommended during pregnancy; consult a healthcare professional for alternatives.
• Breastfeeding - Not advised during breastfeeding; seek medical guidance.
• Liver - Contraindicated in severe liver impairment due to the metformin component.
• Kidney - Contraindicated in severe kidney impairment; dose adjustment needed for moderate impairment.
• Lung - Use with caution in severe respiratory conditions due to potential for lactic acidosis.

Disclaimer

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