DAPANOROM M 10 FORTE 10 S

About

Dapanorom M 10 Forte is a combination oral antidiabetic medication used for the management of type 2 diabetes mellitus. It combines dapagliflozin, an SGLT2 inhibitor, and metformin, a biguanide, offering a complementary approach to glycemic control. Dapagliflozin works by inhibiting the sodium-glucose co-transporter 2 (SGLT2) in the kidneys, leading to increased glucose excretion in the urine and a reduction in blood glucose levels, independent of insulin. Metformin reduces hepatic glucose production, decreases intestinal glucose absorption, and improves insulin sensitivity. This dual mechanism provides comprehensive glycemic control, often leading to additional benefits such as modest weight loss and blood pressure reduction, making it suitable for patients requiring robust glucose management and cardiovascular risk reduction. The "Forte" designation indicates a higher strength formulation, designed for patients needing more intensive therapy.

Uses

• Management of type 2 diabetes mellitus.
• To improve glycemic control in adults.
• When diet and exercise are insufficient.
• To reduce the risk of cardiovascular events in certain patients.

Directions For Use

Take as directed by your physician, usually with meals. Swallow the tablet whole with water.

Benefits

• Effectively lowers blood glucose levels.
• Promotes glucose excretion via the kidneys.
• May contribute to modest weight loss.
• Can help reduce blood pressure.
• Reduces the risk of cardiovascular events.
• Improves insulin sensitivity.

Side Effects

• Genital yeast infections
• Urinary tract infections (UTIs)
• Increased urination
• Thirst
• Hypotension (low blood pressure)
• Ketoacidosis (rare but serious)
• Acute kidney injury
• Nausea
• Diarrhea
• Metallic taste in mouth
• Lactic acidosis (rare but serious)
• Back pain

Safety Measures

• Alcohol - Limit or avoid alcohol due to increased risk of lactic acidosis and potential for dehydration.
• Pregnancy - Not recommended during pregnancy; consult your doctor for safer alternatives.
• Breastfeeding - Avoid use while breastfeeding as components may pass into breast milk.
• Liver - Use with caution in patients with liver impairment; monitor liver function closely.
• Kidney - Contraindicated in severe renal impairment; dose adjustment required for moderate impairment.
• Lung - Exercise caution in severe respiratory conditions due to the risk of lactic acidosis.

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