Adthal 100mg Capsule

Salt Composition: Thalidomide  
Manufacturer: ADLEY FORMULATIONS  
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About

Adthal is a potent immunomodulatory agent, structurally related to thalidomide, known for its diverse pharmacological actions including anti-angiogenic, anti-inflammatory, and direct anti-neoplastic properties. Its complex mechanism of action involves modulating various components of the immune system, influencing cytokine production, and inhibiting the formation of new blood vessels essential for tumor growth and metastasis. Furthermore, Adthal directly impacts the growth and survival of certain cancer cells, particularly in hematological malignancies, by inducing apoptosis and inhibiting cell proliferation. This multifaceted approach makes it a valuable therapeutic option in treating specific conditions characterized by immune dysregulation or uncontrolled cell growth. Its efficacy is attributed to its ability to interfere with multiple cellular pathways, leading to a comprehensive therapeutic effect in conditions like multiple myeloma and certain inflammatory disorders, where it helps to restore immune balance and suppress disease progression.

Uses

  • Treatment of multiple myeloma.
  • Management of certain myelodysplastic syndromes.
  • Treatment of specific inflammatory conditions.
  • Adjunctive therapy in certain dermatological disorders.

Directions For Use

Take orally, usually once daily at bedtime, with water. Follow your doctor's instructions precisely regarding dosage and duration.

Benefits

  • Immunomodulatory effects.
  • Anti-angiogenic properties.
  • Direct anti-tumor activity.
  • Oral administration.
  • Effective in resistant disease.
  • Improved patient outcomes in specific indications.

Side Effects

  • Drowsiness
  • Fatigue
  • Constipation
  • Peripheral neuropathy
  • Rash
  • Thromboembolism
  • Dizziness
  • Tremor
  • Dry skin
  • Nausea
  • Edema
  • Neutropenia

Safety Measures

  • Alcohol - Avoid or limit alcohol consumption as it may increase drowsiness and other central nervous system side effects.
  • Pregnancy - Absolutely contraindicated in pregnancy due to severe teratogenic effects. Strict contraception is mandatory for both male and female patients.
  • Breastfeeding - Breastfeeding is contraindicated due to the potential for serious adverse effects in the infant.
  • Liver - Use with caution in patients with liver impairment; monitor liver function regularly and adjust dose as needed.
  • Kidney - Use with caution in patients with renal impairment; dose adjustments may be necessary based on kidney function.
  • Lung - Monitor for new or worsening pulmonary symptoms, as interstitial lung disease or pneumonitis can occur.

Disclaimer

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Always consult your doctor for any medical concerns, and discuss your questions about health conditions or medications with a qualified healthcare professional. Do not ignore or delay seeking professional medical advice based on information found on Med E Hub.

Our goal is to complement, not replace, the essential doctor-patient relationship.

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